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What is Lyrolin

Lyrolin is an anti-epileptic drug, also called an anticonvulsant. It works by slowing down impulses in the brain that cause seizures. Lyrolin also affects chemicals in the brain that send pain signals across the nervous system.
Lyrolin is used to control seizures and to treat fibromyalgia. It is also used to treat pain caused by nerve damage in people with diabetes, herpes zoster (post-herpetic neuralgia), or spinal cord injury.
Lyrolin may also be used for purposes not listed in Lyrolin guide.

Lyrolin side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive, more depressed, or have thoughts about suicide or hurting yourself.
Call your doctor at once if you have any of these serious side effects:

Less serious side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)

Lyrolin dosing

Usual Adult Dose for Diabetic Neuropathy:

Initial dose: 50 mg 3 times a day
The maximum recommended dose is 100 mg 3 times a day in patients with a creatinine clearance of at least 60 mL/min.
The dose may be increased to 100 mg 3 times a day within 1 week based on efficacy and tolerability.

Usual Adult Dose for Postherpetic Neuralgia:

Initial dose: 75 mg 2 times a day or 50 mg 3 times a day in patients with a creatinine clearance of at least 60 mL/min
The dose may be increased to 100 mg 3 times a day within 1 week based on efficacy and tolerability.
Maximum dose: Patients who do not experience sufficient pain relief following 2 to 4 weeks of treatment with 300 mg/day and who are able to tolerate Lyrolin, may be treated with up to 300 mg 2 times a day or 200 mg 3 times a day. Due to the dose-dependent adverse effects and the higher rate of treatment discontinuation due to adverse events, dosing above 300 mg/day should be reserved only for those patients who have ongoing pain and are tolerating 300 mg daily.

Usual Adult Dose for Epilepsy:

Initial dose: 75 mg 2 times a day or 50 mg 3 times a day
Doses of 150 mg to 600 mg/day have been shown to be effective as adjunctive therapy in the treatment of partial onset seizures. The total daily dose should be divided and given either 2 or 3 times a day.
Maximum dose: Based on individual patient response and tolerability, the dose may be increased to a maximum of 600 mg/day.
The efficacy of add-on Lyrolin in patients taking gabapentin has not been evaluated in controlled trials. Therefore, dosing recommendations for the use of Lyrolin with gabapentin cannot be offered.

Usual Adult Dose for Fibromyalgia:

Initial dose: 75 mg two times a day
The dose may be increased to 150 mg two times a day (300 mg/day) within one week based on efficacy and tolerability.
Patients who do not experience sufficient benefit with 300 mg/day may be further increased to 225 mg two times a day (450 mg/day).
Recommended dose: 300 to 450 mg/day
Although Lyrolin was also studied at 600 mg/day, there is no evidence that this dose confers additional benefit and this dose was less well tolerated. In view of the dose-dependent adverse reactions, treatment with doses above 450 mg/day is not recommended.

Usual Adult Dose for Neuropathic Pain:

For neuropathic pain associated with spinal cord injury:
Initial dose: 75 mg 2 times a day
The dose may be increased to 150 mg 2 times a day within 1 week based on efficacy and tolerability.
Doses of 150 mg to 600 mg/day have been shown to be effective as adjunctive therapy in the treatment of neuropathic pain associated with spinal cord injury. The total daily dose should be divided.
Maximum dose: Patients who do not experience sufficient pain relief following 2 to 3 weeks of treatment with 150 mg 2 times a day and who are able to tolerate Lyrolin, may be treated with up to 300 mg 2 times a day. Because Lyrolin is eliminated primarily by renal excretion, the dose should be adjusted in patients with reduced renal function.

Select the most affordable brand or generic drug

StrengthQuantityPrice, USDCountry
150 mg x 10's $1.89
Gabafit Capsule/ Tablet / 150mg (10 units) $2.00Glenmark Pharmaceuticals (Healtheon Division)
GABAFIT 75MG CAPSULE 1 strip(s) (10 capsules each) $1.09Glenmark Pharmaceuticals Ltd
GABAMAX 750 MCG/75 MG TABLET SR 1 strip(s) (10 tablet srs each) $1.64Aristo Pharmaceuticals Pvt Ltd
Gabamax Pregabalin 150 mg, mecobalamin750 mcg. CAP / 10 $1.96
Gabamax 750 mcg/75 mg Capsule $0.13Aristo Pharmaceuticals Pvt Ltd
150 mg x 10's $2.02
75 mg x 10's $1.07
150 mg10 Capsule$1.81
GALINERVE Capsule/ Tablet / 150mg (10 units) $1.97Sun Pharmaceuticals (Arian Division)
Galinerve Capsule/ Tablet / 75mg (10 units) $1.05Sun Pharmaceuticals (Arian Division)
100 mg60 $225.89USA
200 mg90 $336.34USA
225 mg30 $95.00
300 mg60 $225.89USA
75 mg90 $336.34USA
LYRICA 150 MG CAPSULE 1 strip(s) (14 capsules each) $16.13Pfizer Ltd
Lyrica 75mg CAP / 14 $10.76
Lyrica 75 mg x 56's $86.08
Lyrica 75 mg x 14's $10.74
MAXGALIN 75 MG TABLET ER 1 strip(s) (10 tablet ers each) $1.71Sun Pharma Laboratories Ltd
Maxgalin 150mg CAP / 10 $2.13
50 mg x 10's $0.73
MAXGALIN 50 MG CAPSULE 1 strip(s) (10 capsules each) $1.09Sun Pharma Laboratories Ltd
Neugaba 75mg Capsule $0.18Sun Pharmaceutical Industries Ltd
Neugaba 150mg CAP / 10 $2.07
Neugaba 75 mg Capsule $0.12
75 mg10 Capsule$0.92
150 mg x 10's $2.31
Pregab 150mg CAP / 10 $2.31
75 mg x 10's $1.24
Pregab 75mg CAP / 10 $1.24
Lyrica 200 mg capsule $2.75
Lyrica 225 mg capsule $2.75
Lyrica 25 mg capsule $2.75
Lyrica 300 mg capsule $2.75
Lyrica 100 mg capsule $2.88
Lyrica 150 mg capsule $2.88
Lyrica 50 mg capsule $2.88
Lyrica 75 mg capsule $2.88
100 mg10 Capsule$1.60
Pregalin CAPS 100mg CAP / 10 $1.60
Pregalin CAPS 150mg CAP / 10 $2.31
Pregalin CAPS 75mg CAP / 10 $1.22
Prelin 75mg Capsule $0.14Intas Pharmaceuticals Ltd
PRELIN 150 MG CAPSULE 1 strip(s) (10 capsules each) $1.88Intas Pharmaceuticals Ltd
PRELIN 75 MG CAPSULE 1 strip(s) (10 capsules each) $1.30Intas Pharmaceuticals Ltd


  1. Dailymed."Pregabalin: dailymed provides trustworthy information about marketed drugs in the united states. dailymed is the official provider of fda label information (package inserts).". (accessed August 28, 2018).
  2. "Pregabalin". (accessed August 28, 2018).
  3. "Pregabalin". (accessed August 28, 2018).

Lyrolin - Frequently asked Questions

Can Lyrolin be stopped immediately or do I have to stop the consumption gradually to ween off?

In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.

It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.

What other drugs will affect Lyrolin?

Cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for depression or anxiety can add to dizziness or sleepiness caused by Lyrolin. Tell your doctor if you regularly use any of these medicines, or any other seizure medication.

Tell your doctor about all other medicines you use, especially:

This list is not complete and other drugs may interact with Lyrolin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Who should not take Lyrolin?

You should not use this medication if you are allergic to Lyrolin.

To make sure you can safely take Lyrolin, tell your doctor if you have any of these other conditions:

You may have thoughts about suicide while taking this medication. Tell your doctor if you have new or worsening depression or suicidal thoughts during the first several months of treatment, or whenever your dose is changed.

Your family or other caregivers should also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits. Do not miss any scheduled appointments.

FDA pregnancy category C. It is not known whether Lyrolin will harm an unborn baby, but having a seizure during pregnancy could harm both mother and baby. Tell your doctor right away if you become pregnant while taking Lyrolin for seizures. Do not start or stop taking Lyrolin during pregnancy without your doctor's advice.

If you become pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of Lyrolin on the baby.

It is not known whether Lyrolin passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using Lyrolin.

If a man fathers a child while using this medication, the baby may have birth defects. Use a condom to prevent pregnancy during your treatment.

Do not give this medication to a child younger than 18 years old.

How should I take Lyrolin?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

You may take Lyrolin with or without food.

Measure liquid medicine with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Do not change your dose of Lyrolin without your doctor's advice. Tell your doctor if the medication does not seem to work as well in treating your condition.

Call your doctor if you have any problems with your vision while taking Lyrolin.

If you are taking Lyrolin to prevent seizures, keep taking it even if you feel fine. You may have an increase in seizures if you stop taking Lyrolin. Follow your doctor's instructions.

Do not stop using Lyrolin without first talking to your doctor, even if you feel fine. You may have increased seizures or withdrawal symptoms such as headache, sleep problems, nausea, and diarrhea. Ask your doctor how to avoid withdrawal symptoms when you stop using Lyrolin.

Wear a medical alert tag or carry an ID card stating that you take Lyrolin. Any medical care provider who treats you should know that you take seizure medication.

Store at room temperature away from moisture, light, and heat.

Can Lyrolin be taken or consumed while pregnant?

Please visit your doctor for a recommendation as such case requires special attention.

Can Lyrolin be taken for nursing mothers or during breastfeeding?

Kindly explain your state and condition to your doctor and seek medical advice from an expert.



Following the study conducted by on Lyrolin, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Lyrolin. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.

Patient reports

Patient reported useful

No survey data has been collected yet

Two patients reported side effects

Does the Lyrolin Have Any Side Effects?
Based on the survey report from users of, about No side effects number of people suffered some side effect after consumption of Lyrolin. All drugs have a portion of undesirable side effects. These effects could be irritations too insignificant for the patient to even notice. However, the side effects of drugs may be determined by several factors like severity of disease and conditions associated with individual patients. However, one of the biggest factors is the dosage consumed. The higher the quantity taken by an individual, the greater the healing effect and the corresponding side effect. All patients have their different intensity of side effects. Ensure you consult your health care provider immediately you notice an unusual side effect affect the consumption of Lyrolin.
No side effects2

One patient reported price estimates

Do you think The Price of Lyrolin is Worth It?
Do you feel you paid higher than the value you got from it after usage? According to reports from users, on whether the Lyrolin medicine is affordable, users shared different opinions on the question. The views concerning the price of the medicine were based on some factors like the brand the patient bought, the price compared to its level of effectiveness, the nation or country where the medicine is sold, and the amount of money the patient has. For users who are of the opinion that the medicine is unaffordable, they may have to consider a medicine with another brand in a bid to reduce cost.
Not expensive1

Eight patients reported frequency of use

How often should I take Lyrolin?
According to the survey, reported that users of Lyrolin should take Once in a day as the primarily recommended frequency. However, patients are advised to follow the dosage as prescribed by their physician religiously. To get the opinions of other patients on the ideal consumption frequency of the medicine, click here.
Once in a day4
Twice in a day2
3 times in a day2

Elenen patients reported doses

What is the specific doses you have used?
Lyrolin May come in various doses. In most cases, antibiotics, antihypertensive, pain killers and anti-diabetic drugs available in different doses. Your doctor may prescribe any of the doses based on the severity of the patient's condition. According to our reports, users of used the drugs in the following dosage percentage (Provide dosage percentage). Only a handful of drugs are made in a single or fixed dose. Regular health conditions like fever have similar doses. For instance [acetaminophen, 500mg] was used by the patients surveyed although it comes in different doses.

Four patients reported time for results

How long will I use Lyrolin before I begin to notice the effect?
According to the report by users of, about > 3 month and a few days was the most common time duration among the participants, before they began to feel relief in their health conditions. It is noteworthy that you may not get the same result with other users within the same time frame. Several factors determine the timeframe; hence we implore you to consult your medical expert to get professional advice on how long you should expect to see improvement while consuming Lyrolin. However, if you wish to get the response of other users on the time effectiveness of using Lyrolin kindly click here
> 3 month2
1 day1
1 month1

One patient reported administration

When is the best condition to take Lyrolin: Before or after food?
Based on the survey, the users of voted that Lyrolin is best taken at Before food. It is however worthy of mention that this popular vote may not be an appropriate description for your particular health condition. See your doctor for professional medical advice as regards the best time to take this medicine. If you wish to see the views of other users on the best time to take the medicine, simply click here.
Before food1

Nine patients reported age


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The information was verified by Dr. Vishal Pawar, MD Pharmacology