Treating certain types of cancer. Daxotel is an antineoplastic antibiotic. It works by killing cancer cells.
Important safety information:
Daxotel may reduce the number of clot-forming cells in your blood. To prevent bleeding, avoid situations in which bruising or injury may occur. Report any unusual bleeding, bruising, blood in stools, or dark, tarry stools to your doctor.
Daxotel may lower your body's ability to fight infection. Prevent infection by avoiding contact with people with colds or other infections. Notify your doctor of any signs of infection, including fever, sore throat, rash, or chills.
Do not receive a live vaccine (eg, measles, mumps) while you are taking Daxotel. Talk with your doctor before you receive any vaccine. Daxotel may cause the urine to turn red. This is harmless and usually goes away 1 to 2 days after receiving a dose of Daxotel. Contact your doctor if this continues or if you notice blood in your urine.
Daxotel may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Daxotel. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
Daxotel may cause a serious and possibly fatal condition called tumor lysis syndrome (TLS). Contact your doctor right away if you develop symptoms such as fast or irregular heartbeat; fainting; decreased urination; muscle weakness or cramps; nausea, vomiting, diarrhea, or loss of appetite; or sluggishness. Discuss any questions or concerns with your doctor.
Lab tests, including liver and kidney function, complete blood cell counts, blood uric acid and electrolyte levels, and heart function, may be performed to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
Women who may become pregnant and men who use Daxotel must use an effective form of birth control while they take Daxotel and for at least 6 months after treatment is stopped. Talk to your doctor about birth control methods. If you or your partner becomes pregnant, tell your doctor right away.
Tell your doctor or dentist that you take Daxotel before you receive any medical or dental care, emergency care, or surgery.
Daxotel should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
Caution is advised when using Daxotel in CHILDREN; they may be more sensitive to its effects, especially heart problems (eg, heart failure).
Daxotel may cause infertility that is sometimes permanent. Discuss any questions or concerns with your doctor.
Daxotel may damage sperm. Use effective birth control methods (eg, condoms) while using Daxotel and for 6 months after treatment is stopped. Discuss any questions or concerns with your doctor.
Women using Daxotel may develop absence of menstrual periods or early menopause.
PREGNANCY and BREAST-FEEDING: Daxotel has been shown to cause harm to the fetus. Avoid becoming pregnant while you are using it. If you are able to become pregnant, talk with your doctor about using an effective form of birth control. If you think you may be pregnant, contact your doctor right away. Daxotel is found in breast milk. Do not breast-feed while using Daxotel.
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Daxotel side effects
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Diarrhea; hair loss; nausea; vomiting.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; dizziness; flushed face; tightness in the chest; swelling of the mouth, face, lips, or tongue); absence of menstrual cycle; black, bloody, or tarry stools; chest pain; darkening of nails or separation of nails from the nail bed; fainting; fast, slow, or irregular heartbeat; pain, redness, burning, stinging, swelling, or open sores at the injection site; redness, pain, swelling, peeling, tingling, or blistering of the palms of the hands and the soles of the feet; severe or persistent diarrhea, nausea or vomiting; shortness of breath; sudden, unexplained weight gain; swelling of the hands, ankles, or feet; swelling or soreness of the mouth or tongue; symptoms of dehydration (eg, dry mouth or eyes, decreased urination, fast heartbeat, sluggishness, unusual thirst); symptoms of infection (eg, fever, chills, cough, sore throat, burning or painful urination); unusual bruising or bleeding; unusual tiredness or weakness.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
Dailymed."Doxorubicin hydrochloride: dailymed provides trustworthy information about marketed drugs in the united states. dailymed is the official provider of fda label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
Can Daxotel be stopped immediately or do I have to stop the consumption gradually to ween off?
In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.
It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.
Who should not take Daxotel?
Some medical conditions may interact with Daxotel. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are able to become pregnant
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have liver problems
if you have a history of heart problems (eg, irregular heartbeat), or if you have previously received Daxotel or similar medicines (eg, epirubicin, daunorubicin)
if you are receiving radiation therapy or plan to receive radiation to the chest
if you are taking medicines that may affect heart function (eg, cyclophosphamide, trastuzumab). Ask your doctor if you are unsure if any of your medicines may affect heart function
Some MEDICINES MAY INTERACT with Daxotel. Tell your health care provider if you are taking any other medicines, especially any of the following:
Cyclophosphamide or trastuzumab because the risk of heart problems (eg, heart failure) may be increased
Cyclosporine, paclitaxel, or verapamil because they may increase the risk of doxorubicin's side effects
Phenobarbital, phenytoin, or St. John's wort because they may decrease doxorubicin's effectiveness
Anticoagulants (eg, warfarin) because the risk of their side effects may be increased
Palifermin because if mouth or tongue sores develop, they may be more severe or last longer
Medicines that may harm the liver (eg, acetaminophen, mercaptopurine, methotrexate, ketoconazole, isoniazid, certain medicines for HIV infection) because the risk of doxorubicin's side effects may be increased. Ask your doctor if you are unsure if any of your medicines might harm the liver
This may not be a complete list of all interactions that may occur. Ask your health care provider if Daxotel may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How should I take Daxotel?
Use Daxotel as directed by your doctor. Check the label on the medicine for exact dosing instructions.
An extra patient leaflet is available with Daxotel. Talk to your pharmacist if you have questions about this information.
Daxotel is usually administered as an injection at your doctor's office, hospital, or clinic. Ask your doctor any questions that you may have about Daxotel.
Do not use Daxotel if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
Drinking extra fluids while you are using Daxotel is recommended. Check with your doctor for instructions.
Your doctor may prescribe another medicine to lessen nausea and vomiting that can occur when using Daxotel. Discuss any questions with your doctor.
If you spill Daxotel on your skin, wash it off right away with soap and water and contact your doctor.
Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor or pharmacist to explain local regulations for proper disposal.
If you miss a dose of Daxotel, contact your doctor immediately.
Ask your health care provider any questions you may have about how to use Daxotel.
Can Daxotel be taken or consumed while pregnant?
Please visit your doctor for a recommendation as such case requires special attention.
Can Daxotel be taken for nursing mothers or during breastfeeding?
Kindly explain your state and condition to your doctor and seek medical advice from an expert.
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Reviews
Following the study conducted by gmedication.com on Daxotel, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Daxotel. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.
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