Treating high blood pressure in the lungs (pulmonary arterial hypertension [PAH]. It may also be used for other conditions as determined by your doctor. Zydalis (20 mg) is a phosphodiesterase type 5 (PDE5) inhibitor. It works by relaxing and dilating the vessels in the lungs. This lowers the blood pressure in the lungs and helps to improve your ability to exercise.
Important safety information:
Zydalis may cause dizziness, drowsiness, fainting, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Zydalis (20 mg) with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Zydalis (20 mg) may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
Do not drink large amounts of alcohol (eg, 4 or 5 drinks or more) while you take Zydalis (20 mg). Doing so may increase your risk of dizziness, headache, fast heartbeat, and low blood pressure.
Patients with heart problems who take Zydalis (20 mg) may be at increased risk for heart-related side effects, including heart attack or stroke. Symptoms of a heart attack may include chest, shoulder, neck, or jaw pain; numbness of an arm or leg; severe dizziness, headache, nausea, stomach pain, or vomiting; fainting; or vision changes. Symptoms of a stroke may include confusion; vision or speech changes; one-sided weakness; or fainting. Contact your doctor or seek medical attention right away if you experience these symptoms.
Zydalis (20 mg) may rarely cause a prolonged (eg, longer than 4 hours) or painful erection. This could happen even when you are not having sex. If this is not treated right away, it could lead to permanent sexual problems such as impotence. Contact your doctor right away if this happens.
Zydalis (20 mg) may uncommonly cause mild, temporary vision changes (eg, blurred vision, sensitivity to light, blue/green color tint to vision). Contact your doctor if vision changes persist or are severe.
Rarely, an eye problem called nonarteritic anterior ischemic optic neuropathy (NAION) has been reported in patients who took Zydalis (20 mg). This may lead to decreased vision or permanent loss of vision in some cases. If you notice a sudden decrease in vision or loss of vision in one or both eyes, contact your doctor right away.
Sudden decreases in hearing and loss of hearing have been reported in some patients who have taken Zydalis (20 mg). Sometimes they also noticed ringing in the ears or dizziness. If you notice a sudden decrease or loss of hearing, contact your doctor right away.
Do not use medicines or treatments for ED while you are taking Zydalis (20 mg) without first checking with your doctor.
Use Zydalis (20 mg) with caution in the ELDERLY; they may be more sensitive to its effects.
Use Zydalis (20 mg) with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Zydalis (20 mg) while you are pregnant. It is not known if Zydalis (20 mg) is found in breast milk. If you are or will be breast-feeding while you use Zydalis (20 mg), check with your doctor. Discuss any possible risks to your baby.
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Zydalis (20 mg) side effects
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Flushing; headache; heartburn; mild pain in the arms, legs, or back; muscle pain; nausea; stomach upset; stuffy nose.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; confusion; fainting; fast or irregular heartbeat; memory loss; numbness in arm or leg; one-sided weakness; prolonged, painful erection; red, swollen, blistered, or peeling skin; ringing in the ears; seizures; severe or persistent back or muscle pain; severe or persistent dizziness; severe or persistent vision changes; shortness of breath or wheezing; slurred speech; sudden decrease or loss of hearing; sudden decrease or loss of vision in one or both eyes; sudden, severe headache or vomiting.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
Dailymed."Tadalafil: dailymed provides trustworthy information about marketed drugs in the united states. dailymed is the official provider of fda label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
Can Zydalis (20 mg) be stopped immediately or do I have to stop the consumption gradually to ween off?
In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.
It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.
How should I take Zydalis (20 mg)?
Use Zydalis (20 mg) as directed by your doctor. Check the label on the medicine for exact dosing instructions.
An extra patient leaflet is available with Zydalis (20 mg). Talk to your pharmacist if you have questions about this information.
Take Zydalis (20 mg) by mouth with or without food.
Zydalis (20 mg) works best if it is taken at the same time each day.
Check with your doctor before you eat grapefruit or drink grapefruit juice while you are taking Zydalis (20 mg).
If you miss a dose of Zydalis (20 mg), take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Zydalis (20 mg).
Who should not take Zydalis (20 mg)?
Some medical conditions may interact with Zydalis (20 mg). Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have a history of a prolonged (more than 4 hours) or painful erection (priapism)
if you have a deformed penis (eg, Peyronie disease, cavernosal fibrosis), certain blood cell problems (eg, sickle cell anemia, leukemia, multiple myeloma), or other conditions that may increase the risk of a prolonged or painful erection (priapism)
if you have low blood pressure, uncontrolled high blood pressure, blood vessel problems, angina (chest pain), heart problems (eg, heart valve disease, congestive heart failure, irregular heartbeat) or a history of these conditions
if you have a history of heart attack, stroke, life-threatening irregular heartbeat, liver or kidney problems, dialysis, ulcers, or bleeding problems
if you have a history of eye or vision problems (eg, decreased vision or vision loss, optic nerve problems, retina problems) or hearing problems (eg, ringing in the ears, decreased hearing, hearing loss)
if you take medicine for erectile dysfunction (ED)
Some MEDICINES MAY INTERACT with Zydalis (20 mg). Tell your health care provider if you are taking any other medicines, especially any of the following:
Alpha-blockers (eg, doxazosin), medicines for high blood pressure, or nitrates (eg, isosorbide, nitroglycerin) because severe low blood pressure with dizziness, lightheadedness, and fainting may occur
Azole antifungals (eg, itraconazole, ketoconazole), HIV protease inhibitors (eg, ritonavir), macrolide antibiotics (eg, erythromycin), or telithromycin because they may increase the risk of tadalafil's side effects
Barbiturates (eg, phenobarbital), bosentan, carbamazepine, hydantoins (eg, phenytoin), or rifampin because they may decrease tadalafil's effectiveness
This may not be a complete list of all interactions that may occur. Ask your health care provider if Zydalis (20 mg) may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Can Zydalis (20 mg) be taken or consumed while pregnant?
Please visit your doctor for a recommendation as such case requires special attention.
Can Zydalis (20 mg) be taken for nursing mothers or during breastfeeding?
Kindly explain your state and condition to your doctor and seek medical advice from an expert.
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Reviews
Following the study conducted by gmedication.com on Zydalis (20 mg), the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Zydalis (20 mg). We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.
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