Prizma

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• Read drug prescription
• What is Prizma
• Prizma side effects
• Prizma dosing
• Select the most affordable brand or generic drug
• Frequently asked Questions
• What other drugs will affect Prizma?
• How should I take Prizma?
• Who should not take Prizma?
• Prizma reviews

Read drug prescription

What is Prizma

Prizma is a selective serotonin reuptake inhibitors antidepressant. Prizma affects chemicals in the brain that may become unbalanced and cause depression, panic, anxiety, or obsessive-compulsive symptoms.
Prizma is used to treat major depressive disorder, bulimia nervosa (an eating disorder) obsessive-compulsive disorder, panic disorder, and premenstrual dysphoric disorder (PMDD).
Prizma is sometimes used together with another medication called olanzapine (Zyprexa). to treat depression caused by bipolar disorder (manic depression). This combination is also used to treat depression after at least 2 other medications have been tried without successful treatment of symptoms.
Prizma may also be used for purposes not listed in Prizma guide.

Prizma side effects

Get emergency medical help if you have any of these signs of an allergic reaction: skin rash or hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.
Call your doctor at once if you have:

• blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
• high levels of serotonin in the body--agitation, hallucinations, fever, fast heart rate, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination, fainting;
• low levels of sodium in the body--headache, confusion, slurred speech, severe weakness, vomiting, loss of coordination, feeling unsteady;
• severe nervous system reaction--very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out; or
• severe skin reaction--fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Common side effects may include:

• sleep problems (insomnia), strange dreams;
• headache, dizziness, vision changes;
• tremors or shaking, feeling anxious or nervous;
• pain, weakness, yawning, tired feeling;
• upset stomach, loss of appetite, nausea, vomiting, diarrhea;
• dry mouth, sweating, hot flashes;
• changes in weight or appetite;
• stuffy nose, sinus pain, sore throat, flu symptoms; or
• decreased sex drive, impotence, or difficulty having an orgasm.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)

Prizma dosing

Usual Adult Dose for Bulimia:

Immediate-release oral formulations:
Recommended dose: 60 mg orally once a day
Comments:
-Some patients may need to be started at a lower dose and titrated up over several days to the recommended dose
-Daily doses greater than 60 mg have not been systematically studied for the treatment of Bulimia
Use: Acute and maintenance treatment of binge-eating and vomiting behaviors in moderate to severe Bulimia Nervosa.

Usual Adult Dose for Depression:

Immediate-release oral formulations:
Initial dose: 20 mg orally once a day, increased after several weeks if insufficient clinical improvement is observed
Maintenance dose: 20 to 60 mg orally per day
Maximum dose: 80 mg orally per day
Delayed release oral capsules:
Initial dose: 90 mg orally once a week, commenced 7 days after the last daily dose of immediate-release Prizma 20 mg formulations.
Comments:
-Doses above 20 mg per day may be given in divided doses, in the morning and at noon
-The full effect may be delayed until after at least 4 weeks of treatment
-If a satisfactory response with the once weekly oral Prizma is not maintained, a change back to daily Prizma dosing using the immediate-release oral formulations should be considered.
-Acute episodes of Major Depressive Disorder require several months or longer of sustained pharmacologic therapy
-Whether the dose needed to induce remission is the same as the dose needed to maintain and/or sustain euthymia is unknown
Use: Acute and maintenance treatment of Major Depressive Disorder

Usual Adult Dose for Obsessive Compulsive Disorder:

Immediate-release oral formulations:
Initial dose: 20 mg orally once a day, increased after several weeks if insufficient clinical improvement is observed.
Maintenance dose: 20 to 60 mg orally per day
Maximum dose: 80 mg orally per day
Comments:
-Doses above 20 mg per day may be given in divided doses, in the morning and at noon
-The full effect may be delayed until after at least 5 weeks of treatment
Use: Acute and maintenance treatment of obsessions and compulsions in patients with Obsessive Compulsive Disorder (OCD)

Usual Adult Dose for Panic Disorder:

Immediate-release oral formulations:
Initial dose: 10 mg orally once a day, increased after one week to 20 mg orally once a day
Maintenance dose: 20 to 60 mg orally per day
Maximum dose: 60 mg orally per day
Comments:
-Doses above 20 mg per day may be given in divided doses, in the morning and at noon
-A dose increase may be considered after several weeks if no clinical improvement is observed.
-Doses greater than 60 mg per day have not been systematically studied for the treatment of Panic Disorder
Use: Acute treatment of Panic Disorder

Usual Adult Dose for Premenstrual Dysphoric Disorder:

Immediate-release oral formulations:
Initial dose:
Continuous regimen: 20 mg orally once a day on every day of the menstrual cycle
Cyclic regimen: 20 mg orally once a day starting 14 days prior to the anticipated start of menstruation through to the first full day of menses, and repeated with each new cycle
Maintenance dose: 20 to 60 mg per day for either the continuous or intermittent regimens
Maximum dose: 80 mg orally per day
Duration: The 20 mg daily dosage has been shown to be effective for up to 6 months of treatment
Comments:
-A daily dose of 60 mg has not been shown to be significantly more effective than 20 mg daily
-Daily doses above 60 mg have not been systematically studied in patients with this condition

Usual Pediatric Dose for Depression:

Immediate-release oral formulations:
8 to 18 years:
Initial dose: 10 to 20 mg orally once a day; the 10 mg daily dose may be increased after one week to 20 mg orally once a day
Lower weight children:
Initial dose: 10 mg orally once a day, increased to 20 mg orally once a day after several weeks if insufficient clinical improvement is observed
Maintenance dose: 10 to 20 mg orally once a day
Comments:
-The full effect may be delayed until after at least 4 weeks of treatment
-The potential risks versus clinical need should be assessed prior to using this drug in children and adolescents
Use: Acute and maintenance treatment of Major Depressive Disorder

Usual Pediatric Dose for Obsessive Compulsive Disorder:

7 to 18 years:
Immediate-release oral formulations:
Adolescents and higher weight children:
Initial dose: 10 mg orally once a day, increased to 20 mg orally once a day after 2 weeks
Maintenance dose: 20 to 60 mg orally per day
Maximum dose: 60 mg orally per day
Lower weight children:
Initial dose: 10 mg orally once a day, increased after several weeks if insufficient clinical improvement is observed
Maintenance dose: 20 to 30 mg orally once a day
Maximum dose: 60 mg orally per day
Comments:
-Additional dose increases may be considered after several more weeks if clinical improvement is insufficient
-Doses above 20 mg per day may be given in divided doses, in the morning and at noon
-In lower weight children, there is minimal experience with doses greater than 20 mg per day, and none with doses greater than 60 mg per day
-The full effect may be delayed until after at least 5 weeks of treatment
-The potential risks versus clinical need should be assessed prior to using this drug in children and adolescents
Use: Acute and maintenance treatment of obsessions and compulsions in patients with Obsessive Compulsive Disorder

Active ingredients: Fluoxetine

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Strength	Quantity	Price, USD	Country
Actisac
Andepin
Ansi
Ao Mai Lun
Aprinol
Arrow Fluoxetine
Clinium
Clinium 60 mg Tablet		$0.02
Clinium 150 mg x 100's		$20.35
Clinium 300 mg x 100's		$31.45
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Deprozin
Docfluoxetine
Elizac
Elizac 20 mg x 5 x 6's		$8.88
Equiflox
Equilibrane
FXT
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Fluoxetin-ratiopharm
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Fluoxetine Hydrochloride Pharmaceutical Associates
Fluoxetine Niche
Fluoxetine solution
Fluoxétine Isomed
Fluoxétine LBR
Fluoxétine Teva Sante
Foransi
Foransi 20 mg x 3 x 10's		$9.99
Foransi 10 mg x 3 x 10's		$6.66
Gerozac
Ladose
Loftil
20 mg x 10's		$0.38
Loftil 20mg CAP / 10		$0.38
LOFTIL cap 20 mg x 10's		$0.38	AHPL
LOFTIL Capsule/ Tablet / 20mg (10 units)		$0.38	Nicholas Piramal
Neuro Laz
Nuzac
NUZAC cap 10 mg x 10's		$0.16	Cipla (Protec)
20 mg x 10's		$0.28
Oxactin
Prodep
10 mg x 10's		$0.38
Prodep 20mg/5mL SUSP / 1		$0.42
PRODEP 20 MG SUSPENSION 1 bottle(s) (60 ML suspension each)		$0.52	Sun Pharma Laboratories Ltd
20 mg x 10's		$0.62
PRODEP Capsule/ Tablet / 60mg (10 units)		$1.21	Sun Pharmaceuticals
RAN-Fluoxetine
Reconcile
Riva-Fluoxetine
Saurat
Uxetine
Xetin
Xetin 20 mg Capsule		$0.03
Zyflo IR
600 mg	30	$299.00	Israel
600 mg	120	$1.00	Australia, Canada, NZ, Singapore, Turkey, UK, USA
600 mg	120	$1.00	Australia, Canada, India, Mauritius, NZ, Turkey, UK, USA
600 mg	120	$1.00	Australia, Canada, India, Mauritius, NZ, Turkey, Singapore, UK, USA
600 mg	120	$1.00	Australia, Canada, India, Mauritius, NZ, Singapore, Turkey, UK, USA

References

1. "Fluoxetine". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
2. "Fluoxetine". http://www.drugbank.ca/drugs/DB0047... (accessed August 28, 2018).
3. "Nsc283480: the nci development therapeutics program (dtp) provides services and resources to the academic and private-sector research communities worldwide to facilitate the discovery and development of new cancer therapeutic agents.". https://dtp.cancer.gov/dtpstandard/... (accessed August 28, 2018).

Prizma - Frequently asked Questions

Can Prizma be stopped immediately or do I have to stop the consumption gradually to ween off?

In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.

It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.

What other drugs will affect Prizma?

Taking this medicine with other drugs that make you sleepy can worsen this effect. Ask your doctor before taking Prizma with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.

Many drugs can interact with Prizma. Not all possible interactions are listed here. Tell your doctor about all your medications and any you start or stop using during treatment with Prizma, especially:

• any other antidepressant;

• St. John's Wort;

• tramadol;

• tryptophan (sometimes called L-tryptophan);

• a blood thinner--warfarin, Coumadin, Jantoven;

• medicine to treat mood disorders, thought disorders, or mental illness--amitriptyline, desipramine, lithium, nortriptyline, and many others;

• migraine headache medicine--rizatriptan, sumatriptan, zolmitriptan, and others; or

• narcotic pain medicine--fentanyl, tramadol.

This list is not complete and many other drugs can interact with Prizma. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

How should I take Prizma?

Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Do not crush, chew, break, or open a delayed-release capsule. Swallow it whole.

Measure liquid medicine with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

It may take up to 4 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve.

Do not stop using Prizma suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using Prizma.

To treat premenstrual dysphoric disorder, the usual dose of Prizma is once daily while you are having your period, or 14 days before you expect your period to start. Follow your doctor's instructions.

Store at room temperature away from moisture and heat.

Who should not take Prizma?

Do not use Prizma if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine. You must wait at least 14 days after stopping an MAO inhibitor before you can take Prizma. You must wait 5 weeks after stopping Prizma before you can take thioridazine or an MAOI.

You should not use Prizma if you are allergic to it, if you also take pimozide or thioridazine, or if you are being treated with methylene blue injection.

If you also take olanzapine, read the Zyprexa medication guide and all patient warnings and instructions provided with that medication.

Tell your doctor about all other antidepressants you take, especially Celexa, Cymbalta, Desyrel, Effexor, Lexapro, Luvox, Oleptro, Paxil, Pexeva, Symbyax, Viibryd, or Zoloft.

To make sure Prizma is safe for you, tell your doctor if you have:

• cirrhosis of the liver;

• kidney disease;

• diabetes;

• narrow-angle glaucoma;

• seizures or epilepsy;

• bipolar disorder (manic depression);

• a history of drug abuse or suicidal thoughts; or

• if you are being treated with electroconvulsive therapy (ECT).

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor will need to check your progress at regular visits while you are using Prizma. Your family or other caregivers should also be Prizma to changes in your mood or symptoms.

FDA pregnancy category C. Taking an SSRI antidepressant during pregnancy may cause serious lung problems or other complications in the baby. However, you may have a relapse of depression if you stop taking your antidepressant. Tell your doctor right away if you become pregnant while taking Prizma. Do not start or stop taking this medicine during pregnancy without your doctor's advice.

Prizma can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Do not give this medication to anyone under 18 years old without medical advice.

Can Prizma be taken or consumed while pregnant?

Please visit your doctor for a recommendation as such case requires special attention.

Can Prizma be taken for nursing mothers or during breastfeeding?

Kindly explain your state and condition to your doctor and seek medical advice from an expert.

Reviews

Following the study conducted by gmedication.com on Prizma, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Prizma. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.

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The information was verified by Dr. Vishal Pawar, MD Pharmacology