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Polibutin |
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What is Polibutin
Sunitinib is a cancer medicine that interferes with the growth and spread of cancer cells in the body.Sunitinib is used to treat certain types of advanced or progressive tumors of the digestive system, the pancreas, or the kidneys.
Sunitinib may also be used for purposes not listed in Polibutin guide.
What is the most important information I should know about Polibutin?
Sunitinib can cause severe or fatal effects on your liver. You will need frequent blood tests to check your liver function during treatment. Call your doctor if you have any signs of a liver problem, such as upper stomach pain, itching, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes).Polibutin side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.Sunitinib can cause severe or fatal effects on your liver. Call your doctor if you have:
- liver problems--nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Also call your doctor at once if you have:
- feeling short of breath (even with mild exertion), swelling in your ankles or feet;
- headache with chest pain and severe dizziness, fainting, fast or pounding heartbeats;
- redness, tenderness, sunburn-like peeling of the palms of your hands or the soles of your feet;
- unusual bleeding (nose, mouth, vagina, or rectum);
- signs of bleeding inside your body--change in your mental state, easy bruising, blood in your urine, pain and swelling in your stomach, bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;
- signs of tumor cell breakdown--lower back pain, blood in your urine, little or no urinating; numbness or tingly feeling around your mouth; muscle weakness or tightness; fast or slow heart rate, weak pulse, feeling short of breath; confusion, fainting;
- dangerously high blood pressure--severe headache, blurred vision, pounding in your neck or ears, nosebleed, anxiety, confusion, severe chest pain, shortness of breath, irregular heartbeats, seizure;
- symptoms of a hormone problem--severe tiredness, depression, fast heart rate, agitation, tremors, feeling nervous, sweating, feeling hot, nausea, vomiting, diarrhea, hair loss, irregular menstrual periods; or
- severe skin reaction--fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Common side effects may include:
- indigestion, decreased appetite, stomach pain, nausea, vomiting, diarrhea, constipation;
- muscle or joint pain, headache, feeling weak or tired;
- blisters or ulcers in your mouth, red or swollen gums, altered sense of taste, trouble swallowing;
- increased blood pressure;
- bleeding;
- swelling in your hands or feet;
- cough, trouble breathing; or
- skin rash or dryness, changes in skin or hair color.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
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References
- "Trimebutine". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
- "Trimebutine". http://www.drugbank.ca/drugs/DB0908... (accessed August 28, 2018).
- "Trimebutine maleate: link to the compound information in wikipedia.". https://www.wikidata.org/wiki/Q2725... (accessed August 28, 2018).
Polibutin - Frequently asked Questions
Can Polibutin be stopped immediately or do I have to stop the consumption gradually to ween off?
In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.
It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.
What other drugs will affect Polibutin?
Tell your doctor about all medicines you use, and those you start or stop using during your treatment with sunitinib, especially medicines to treat osteoporosis or Paget's disease, such as:
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risedronate (Actonel);
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pamidronate (Aredia);
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ibandronate (Boniva);
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etidronate (Didronel);
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alendronate (Fosamax);
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tiludronate (Skelid); or
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zoledronic acid (Reclast, Zometa).
This list is not complete. Other drugs may interact with sunitinib, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
Who should not take Polibutin?
You should not use sunitinib if you are allergic to it.
To make sure sunitinib is safe for you, tell your doctor if you have:
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liver or kidney disease;
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heart disease, high blood pressure, heart rhythm disorder;
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seizures;
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a bleeding or blood-clotting disorder;
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a disorder of your thyroid or adrenal gland;
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a personal or family history of Long QT syndrome; or
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a history of stroke, heart attack, congestive heart failure, a blood clot, or coronary artery disease.
In rare cases, this medicine may cause bone loss (osteonecrosis) in the jaw. Symptoms include jaw pain or numbness, red or swollen gums, loose teeth, or slow healing after dental work.
Osteonecrosis of the jaw may be more likely if you have cancer or received chemotherapy, radiation, or steroids. Other risk factors include blood clotting disorders, anemia (low red blood cells), and a pre existing dental problem.
Do not use sunitinib if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment.
It is not known whether sunitinib passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using sunitinib.
How should I take Polibutin?
Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Your blood pressure and liver function may need to be tested at the beginning of each 4-week treatment cycle.
Sunitinib is usually taken once per day. Sunitinib is sometimes taken for 4 weeks followed by 2 weeks off the drug. Your doctor will determine how many complete treatment cycles you need based on your condition.
You may take sunitinib with or without food.
Do not crush, chew, or open a sunitinib capsule. Swallow it whole. The medicine from a crushed or broken pill can be dangerous if it gets on your skin. If this occurs, wash your skin with soap and water and rinse thoroughly.
To be sure this medicine is not causing harmful effects, you will need frequent blood and urine tests. Your heart function may also need to be tested with an electrocardiogram (ECG or EKG) on a regular basis, and you may also need frequent dental exams. Do not miss any follow-up visits to your doctor.
If you need surgery or a dental procedure, tell the surgeon or dentist ahead of time that you are using sunitinib. You may need to stop using the medicine for a short time.
Store at room temperature away from moisture and heat.
Can Polibutin be taken or consumed while pregnant?
Please visit your doctor for a recommendation as such case requires special attention.
Can Polibutin be taken for nursing mothers or during breastfeeding?
Kindly explain your state and condition to your doctor and seek medical advice from an expert.
Reviews
Following the study conducted by gmedication.com on Polibutin, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Polibutin. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.Patient reports
Patient reported useful
No survey data has been collected yetThree patients reported side effects
Does the Polibutin Have Any Side Effects?Based on the survey report from users of gmedication.com, about No side effects number of people suffered some side effect after consumption of Polibutin. All drugs have a portion of undesirable side effects. These effects could be irritations too insignificant for the patient to even notice. However, the side effects of drugs may be determined by several factors like severity of disease and conditions associated with individual patients. However, one of the biggest factors is the dosage consumed. The higher the quantity taken by an individual, the greater the healing effect and the corresponding side effect. All patients have their different intensity of side effects. Ensure you consult your health care provider immediately you notice an unusual side effect affect the consumption of Polibutin.
| Patients | % | ||
|---|---|---|---|
| No side effects | 3 | 100.0% | |
One patient reported price estimates
Do you think The Price of Polibutin is Worth It?Do you feel you paid higher than the value you got from it after usage? According to reports from gmedication.com users, on whether the Polibutin medicine is affordable, users shared different opinions on the question. The views concerning the price of the medicine were based on some factors like the brand the patient bought, the price compared to its level of effectiveness, the nation or country where the medicine is sold, and the amount of money the patient has. For users who are of the opinion that the medicine is unaffordable, they may have to consider a medicine with another brand in a bid to reduce cost.
| Patients | % | ||
|---|---|---|---|
| Not expensive | 1 | 100.0% | |
Two patients reported frequency of use
How often should I take Polibutin?According to the survey, gmedication.com reported that users of Polibutin should take Once in a day as the primarily recommended frequency. However, patients are advised to follow the dosage as prescribed by their physician religiously. To get the opinions of other patients on the ideal consumption frequency of the medicine, click here.
| Patients | % | ||
|---|---|---|---|
| Once in a day | 1 | 50.0% | |
| 3 times in a day | 1 | 50.0% | |
Twelve patients reported doses
What is the specific doses you have used?Polibutin May come in various doses. In most cases, antibiotics, antihypertensive, pain killers and anti-diabetic drugs available in different doses. Your doctor may prescribe any of the doses based on the severity of the patient's condition. According to our reports, users of gmedication.com used the drugs in the following dosage percentage (Provide dosage percentage). Only a handful of drugs are made in a single or fixed dose. Regular health conditions like fever have similar doses. For instance [acetaminophen, 500mg] was used by the patients surveyed although it comes in different doses.
| Patients | % | ||
|---|---|---|---|
| 51-100mg | 6 | 50.0% | |
| 1-5mg | 3 | 25.0% | |
| 201-500mg | 1 | 8.3% | |
| 101-200mg | 1 | 8.3% | |
| 6-10mg | 1 | 8.3% | |
Three patients reported time for results
How long will I use Polibutin before I begin to notice the effect?According to the report by users of gmedication.com, about 1 day and a few days was the most common time duration among the participants, before they began to feel relief in their health conditions. It is noteworthy that you may not get the same result with other users within the same time frame. Several factors determine the timeframe; hence we implore you to consult your medical expert to get professional advice on how long you should expect to see improvement while consuming Polibutin. However, if you wish to get the response of other users on the time effectiveness of using Polibutin kindly click here
| Patients | % | ||
|---|---|---|---|
| 1 day | 1 | 33.3% | |
| 3 days | 1 | 33.3% | |
| > 3 month | 1 | 33.3% | |
Two patients reported administration
When is the best condition to take Polibutin: Before or after food?Based on the survey, the users of gmedication.com voted that Polibutin is best taken at Empty stomach. It is however worthy of mention that this popular vote may not be an appropriate description for your particular health condition. See your doctor for professional medical advice as regards the best time to take this medicine. If you wish to see the views of other users on the best time to take the medicine, simply click here.
| Patients | % | ||
|---|---|---|---|
| Empty stomach | 2 | 100.0% | |
Four patients reported age
| Patients | % | ||
|---|---|---|---|
| > 60 | 3 | 75.0% | |
| 1-5 | 1 | 25.0% | |
Patient reviews
There are no reviews yet. Be the first to write one! |
The information was verified by Dr. Vishal Pawar, MD Pharmacology