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What is Pantoprazole RPG

Pantoprazole RPG is in a group of drugs called Pantoprazole RPG pump inhibitors. It decreases the amount of acid produced in the stomach.
Pantoprazole RPG is used to treat erosive esophagitis, and other conditions involving excess stomach acid such as Zollinger-Ellison syndrome.
Pantoprazole RPG is not for immediate relief of heartburn symptoms.
Pantoprazole RPG may also be used for purposes not listed in Pantoprazole RPG guide.

Pantoprazole RPG side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using Pantoprazole RPG and call your doctor at once if you have symptoms of low magnesium such as:

Less serious side effects are more likely to occur, such as:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)

Pantoprazole RPG dosing

Usual Adult Dose for Erosive Esophagitis:

Treatment of Erosive Esophagitis:
40 mg orally once a day for up to 8 weeks; however an additional 8 weeks may be considered for patients who have not healed after the initial treatment. Safety and efficacy beyond 16 weeks of therapy have not been established.
Maintenance of Healing of Erosive Esophagitis:
40 mg orally once a day. Controlled studies have been limited to 12 months of Pantoprazole RPG therapy.

Usual Adult Dose for Gastroesophageal Reflux Disease:

Parenteral: 40 mg once a day for 7 to 10 days, administered via intravenous infusion over a period of 15 minutes. Intravenous therapy should be discontinued as soon as the patient is able to resume oral therapy.
Oral: 40 mg orally once a day, for short-term administration ; however an additional 8 weeks may be considered for patients who have not healed after the initial treatment. Safety and efficacy beyond 16 weeks of therapy have not been established.

Usual Adult Dose for Duodenal Ulcer:

Study (n=54)
40 mg orally once a day, dose was increased every 12 weeks by 40 mg increments to a maximum of 120 mg per day, for 28 weeks. Data have revealed that monotherapy with daily doses of 40 mg have been associated with complete duodenal ulcer healing in up to 87% and 94% of patients after 4 weeks and 8 weeks respectively.

Usual Adult Dose for Gastric Ulcer:

40 mg orally once a day. Data have revealed that monotherapy with daily doses of 40 mg have been associated with complete gastric ulcer healing in up to 87% and 97% of patients after 4 weeks and 8 weeks respectively.

Usual Adult Dose for Helicobacter pylori Infection:

Study - Triple therapy:
40 mg orally twice daily for 7 days, commonly in conjunction with clarithromycin and either amoxicillin or metronidazole to eradicate Helicobacter pylori, followed with 40 mg Pantoprazole RPG orally once daily until day 28. Triple therapy has resulted in eradication rates of greater than 95%.
The QUADRATE Study (n=405) - Quadruple therapy:
40 mg orally twice daily for 7 days, concomitantly with bismuth subcitrate and tetracycline, both four times daily, and metronidazole 200 mg three times daily and 400 mg at bedtime. Helicobacter Pylori eradication was achieved in 82% of patients.

Usual Adult Dose for Zollinger-Ellison Syndrome:

Parenteral: 80 mg every 12 hours, administered by 15-minute infusion. Daily doses higher than 240 mg administered in equally divided doses by 15-minute infusion, or administered for more than 6 days have not been studied.
Oral: 40 mg twice daily, to a maximum of 240 mg per day. Some patients have received treatment with Pantoprazole RPG for more than 2 years.

Usual Adult Dose for Stress Ulcer Prophylaxis:

Study - Stress Ulcer bleeding prophylaxis in the Critical Care Setting:
80 mg twice daily, as a bolus infusion over a period of 15 minutes, to a maximum daily dose of 240 mg, divided into three equal doses.
Study (n=20 ) - Peptic Ulcer rebleeding prophylaxis after hemostasis in the Critical Care Setting:
80 mg IV bolus, followed by continuous infusion of 8 mg/hr for 3 days, after which therapy may be continued with an oral PPI.

Usual Adult Dose for Peptic Ulcer:

Study (n=21) - Stress Ulcer bleeding prophylaxis in the Critical Care Setting:
80 mg twice daily, as a bolus infusion over a period of 15 minutes, to a maximum daily dose of 240 mg, divided into three equal doses.
Study (n=20 ) - Peptic Ulcer rebleeding prophylaxis after hemostasis in the Critical Care Setting:
80 mg IV bolus, followed by continuous infusion of 8 mg/hr for 3 days, after which therapy may be continued with an oral PPI.

Select the most affordable brand or generic drug


StrengthQuantityPrice, USDCountry
40 mg x 10's $0.66
ASOPRAZOLE tab 40 mg x 10's $0.66AS Pharma
Asoprazole 40mg TAB / 10 $0.66
Cool Pan 40 mg Tablet $0.07
40 mg x 10's $0.73
Cool Pan 40mg TAB / 10 $0.73
40 mg10 Tablet$0.67
40 mg x 10's $0.64
P-ZOLE tab 40 mg x 10's $0.64Zenon
P-ZOLE 40mg TAB / 10 $0.64
40 mg x 1's $0.77
P-ZOLE 40mg INJ / 1 $0.77
40 mg x 10ml $0.77
Panpra 40mg VIAL / 10ml $0.77
Pansa 40mg Injection $0.08Zuventus Healthcare Ltd
Pansa 40mg VIAL / 1 $0.78
Pansa 40mg Tablet $0.12Zuventus Healthcare Ltd
PANTAZ 40 MG TABLET 1 strip(s) (10 tablets each) $0.54Medley Pharmaceuticals
40 mg x 10's $0.69
PANTAZ tab 40 mg x 10's $0.69Medley
Pantaz 40ng TAB / 10 $0.69
PANTAZ Capsule/ Tablet / 40mg (10 units) $0.69Medley Pharmaceuticals
Pantodac 40mg Injection $0.06Zydus Cadila
PANTODAC enteric-coated tab 20 mg x 10's $0.76Zydus (Alidac)
PANTODAC enteric-coated tab 40 mg x 10's $1.12Zydus (Alidac)
20 mg84 $28.00Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
20 mg84 $66.36Barbados, Canada, NZ, UK
20 mg84 $96.96Australia, Canada, India, Mauritius, NZ, Turkey, UK, USA
20 mg100 $365.04USA
20 mg112 $29.00Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
20 mg112 $29.00Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
20 mg224 $39.00Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
40 mg28 $35.60Barbados, Canada, NZ, UK
40 mg30 $69.08Canada, UK
40 mg84 $79.80Barbados, Canada, NZ, UK
40 mg90 $59.90USA
40 mg100 $28.00Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
40 mg100 $49.00Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
40 mg100 $75.00Australia, Canada, India, Mauritius, NZ, Singapore, Turkey, UK, USA
40 mg100 $85.05Australia, Canada, India, NZ, Singapore, Turkey, UK, USA
Novo-Pantoprazole 40 mg Enteric-Coated Tablet $1.27
Sandoz Pantoprazole 40 mg Enteric-Coated Tablet $1.27
Pantoprazole Sodium 20 mg Enteric Coated Tabs $4.26
Protonix 40 mg Enteric Coated Tabs $5.43
Pantoprix 40 mg x 2 x 7's $17.50
Pantoprix enteric film-coated tab 40 mg 2 x 7's $17.50Shou Chan
40 mg x 10's $0.64
PANTOTAB tab 40 mg x 10's $0.64Micro Nova
Pantotab 40mg TAB / 10 $0.64
PANTOTAB Capsule/ Tablet / 40mg (10 units) $0.70Micro Nova Pharmaceuticals
40 mg x 1's $0.81
Pantotab 40mg INJ / 1 $0.81
PANTOTAB 40 MG INJECTION 1 vial(s) (10 ML injection each) $0.89Micro Labs Ltd
Pantotab 40mg Tablet $0.11Micro Labs Ltd
PANTOTAB 40 MG TABLET 1 strip(s) (10 tablets each) $1.13Micro Labs Ltd
40 mg x 10's $0.77
PEBLO tab 40 mg x 10's $0.77Aden Healthcare
Peblo 40mg TAB / 10 $0.77
40 mg x 1's $0.81
Peblo 40mg VIAL / 1 $0.81
40 mg x 1's $0.84
Pintel 40mg VIAL / 1 $0.84
Pnx 40mg Tablet $0.07Health Care Formulations Pvt Ltd
PNX 40MG TABLET 1 strip(s) (10 tablets each) $0.70Health Care Formulations Pvt Ltd
PNX enteric-coated tab 40 mg x 10's $0.70Health Care
40 mg x 100's $7.00
PNX 40mg EC-TAB / 100 $7.00
40 mg x 1's $0.80
PNX 40mg VIAL / 1 $0.80
Protopan 20mg Tablet $0.06East West Pharma
20 mg x 10's $0.63
PROTOPAN 20MG TABLET 1 strip(s) (10 tablets each) $0.63East West Pharma
PROTOPAN coated tab 20 mg x 10's $0.63East West
Protopan 20mg TAB / 10 $0.63
40 mg x 10's $0.73
PROTOPAN coated tab 40 mg x 10's $0.73East West
Protopan 40mg TAB / 10 $0.73
40 mg x 1's $0.77
Protopan 40mg VIAL / 1 $0.77
Rcpan 40mg Tablet $0.06SRK Lifesciences & Research India Pvt Ltd
RCPAN tab 40 mg x 10's $0.63SRK
40 mg10 Tablet$0.56
40 mg30 $45.60Barbados, Canada, NZ, UK
40 mg90 $109.80Barbados, Canada, NZ, UK
40 mg90 $109.80Barbados, Canada, NZ, UK

References

  1. "Pantoprazole". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
  2. "Pantoprazole". http://www.drugbank.ca/drugs/DB0021... (accessed August 28, 2018).
  3. "Pantoprazole: the nci development therapeutics program (dtp) provides services and resources to the academic and private-sector research communities worldwide to facilitate the discovery and development of new cancer therapeutic agents.". https://dtp.cancer.gov/dtpstandard/... (accessed August 28, 2018).

Pantoprazole RPG - Frequently asked Questions

Can Pantoprazole RPG be stopped immediately or do I have to stop the consumption gradually to ween off?

In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.

It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.

Who should not take Pantoprazole RPG?

Heartburn is often confused with the first symptoms of a heart attack. Seek emergency medical attention if you have chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, and a general ill feeling.

You should not take this medication if you are allergic to Pantoprazole RPG or to any other benzimidazole medication such as albendazole, or mebendazole (Vermox).

To make sure you can safely take Pantoprazole RPG, tell your doctor if you low levels of magnesium in your blood.

Some conditions must be treated long-term with Pantoprazole RPG. The chronic use of Pantoprazole RPG has caused stomach cancer in animal studies, but it is not known if this medication would have the same effects in humans. Talk with your doctor about your specific risk of developing stomach cancer.

Taking a Pantoprazole RPG pump inhibitor such as Pantoprazole RPG may increase your risk of bone fracture in the hip, wrist, or spine. This effect has occurred mostly in people who have taken the medication long term or at high doses, and in those who are age 50 and older. It is not clear whether Pantoprazole RPG is the actual cause of an increased risk of fracture. Before you take this medication, tell your doctor if you have osteoporosis or osteopenia (low bone mineral density).

Long-term treatment with Pantoprazole RPG may also make it harder for your body to absorb vitamin B-12, resulting in a deficiency of this vitamin. Symptoms of a vitamin B-12 deficiency may develop slowly and include pale skin, weakness, tired feeling, shortness of breath, and a fast heart rate. Talk with your doctor if you need long-term Pantoprazole RPG treatment and you have concerns about vitamin B-12 deficiency.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Pantoprazole RPG can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

What other drugs will affect Pantoprazole RPG?

Pantoprazole RPG should not be taken together with atazanavir (Reyataz) or nelfinavir (Viracept). Tell your doctor if you are taking either of these medications to treat HIV or AIDS.

Tell your doctor about all other medicines you use, especially:

This list is not complete and other drugs may interact with Pantoprazole RPG. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

How should I take Pantoprazole RPG?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Pantoprazole RPG tablets can be taken with or without food. Pantoprazole RPG oral granules should be taken 30 minutes before a meal.

Do not crush, chew, or break the tablet. Swallow it whole. The enteric-coated pill has a special coating to protect your stomach. Breaking the pill will damage this coating.

The oral granules should be mixed only with applesauce or apple juice to make swallowing easy. Do not use any other type of liquid or soft food. Sprinkle the granules directly onto a teaspoon of applesauce and swallow this mixture right away without chewing. Or pour the granules into a cup with 1 teaspoon of apple juice, stir for 5 seconds and swallow right away. To make sure you get the entire dose, add a little more apple juice to the same glass, swirl gently and drink right away. Do not save the granule mixture for later use.

To give Pantoprazole RPG granules through a nasogastric (NG) feeding tube:

This medication can cause you to have a false positive drug-screening test. If you provide a urine sample for drug-screening, tell the laboratory staff that you are taking Pantoprazole RPG.

Take this medication for the full prescribed length of time. Your symptoms may improve before the condition is fully treated.

Call your doctor if your symptoms do not improve or if they get worse while you are taking this medicine.

Store at room temperature away from moisture and heat.

Can Pantoprazole RPG be taken or consumed while pregnant?

Please visit your doctor for a recommendation as such case requires special attention.

Can Pantoprazole RPG be taken for nursing mothers or during breastfeeding?

Kindly explain your state and condition to your doctor and seek medical advice from an expert.

Reviews

Following the study conducted by gmedication.com on Pantoprazole RPG, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Pantoprazole RPG. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.

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The information was verified by Dr. Vishal Pawar, MD Pharmacology