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Here is the some steps to help you to save money on Lutofolone purchase.

Read drug prescription

It is very important to know about what medicine is given by the doctor, for what condition, and when it needs to be taken in what dose. This information given by the doctor is called Prescription. The patients should be familiar with the medicine prescription, and the details about the medicine before purchasing it and using it. Some medications need not be prescribed by healthcare practitioners and can be purchased and used without prescription by the patients; these are called over-the-counter medications. Read the drug prescription information of Lutofolone before taking it.

consists of Estradiol, Progesterone.

Estradiol (Lutofolone)

What is Estradiol (Lutofolone)

Treating itching, burning, and dryness in or around the vaginal area in women past menopause.
Estradiol (Lutofolone) is a vaginal estrogen tablet. It works by increasing the amount of estrogen in the body in certain women who do not produce enough on their own.

Important safety information:

  • Estradiol may increase the risk of stroke, heart attack, blood clots, high blood pressure, or similar problems. The risk may be greater if you smoke.
  • Estradiol (Lutofolone) may cause dark skin patches on your face (melasma). Exposure to the sun may make these patches darker, and you may need to avoid prolonged sun exposure and sunlamps. Consult your doctor regarding the use of sunscreens and protective clothing.
  • Tell your doctor or dentist that you take Estradiol (Lutofolone) before you receive any medical or dental care, emergency care, or surgery. If you will be having surgery or will be confined to a chair or bed for a long period of time (eg, a long plane flight), notify your doctor at least 4 to 6 weeks beforehand. You may need to stop taking Estradiol (Lutofolone) or take other special precautions for a period of time.
  • If you wear contact lenses and you develop problems with them, contact your doctor.
  • Diabetes patients - Estradiol (Lutofolone) may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
  • Estradiol (Lutofolone) may interfere with certain lab tests. Be sure your doctor and lab personnel know you are using Estradiol (Lutofolone).
  • Lab tests, including physical exams, cholesterol levels, and blood pressure, may be performed while you use Estradiol (Lutofolone). You should have breast and pelvic exams and a Pap test at least once a year. You should also have periodic mammograms as determined by your doctor. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Follow your doctors instructions for examining your breasts, and report any lumps immediately.
  • Talk with your doctor regularly (eg, every 3 to 6 months) about whether you need to continue taking Estradiol (Lutofolone).
  • Use Estradiol (Lutofolone) with caution in the ELDERLY; they may be more sensitive to its effects.
  • Estradiol (Lutofolone) is not approved for use in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: Do not use Estradiol (Lutofolone) if you are pregnant. If you think you may be pregnant, contact your doctor right away. Estradiol (Lutofolone) is found in breast milk. If you are or will be breast-feeding while you use Estradiol (Lutofolone), check with your doctor. Discuss any possible risks to your baby.

Estradiol (Lutofolone) side effects

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
  • Breast pain or tenderness; diarrhea; hair loss; headache; mild fluid retention; mild nausea or vomiting; spotting or breakthrough bleeding; stomach cramps or bloating.
  • Seek medical attention right away if any of these SEVERE side effects occur:
  • Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); abnormal vaginal bleeding; breast lumps or pain; bulging eyes; calf pain, swelling, or tenderness; chest pain; coughing up blood; fainting; mental or mood changes (eg, depression); migraine headache; new or worsening memory problems; new or worsening vaginal pain or irritation; pelvic pain; severe or persistent dizziness or headache; severe or persistent stomach or back pain (with or without nausea or vomiting); shortness of breath; swelling of the hands or feet; symptoms of heart attack (eg, chest, jaw, or arm pain; sudden, severe nausea or vomiting; shortness of breath; sudden, unusual sweating); symptoms of liver problems (eg, dark urine, pale stools, yellowing of the skin or eyes); symptoms of stroke (eg, one-sided weakness, slurred speech, confusion); unusual vaginal discharge/itching/odor; vision loss or other vision changes; vomiting.

  • This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

    Progesterone (Lutofolone)

    What is Progesterone (Lutofolone)

    Progesterone (Lutofolone) is a female hormone important for the regulation of ovulation and menstruation.
    Progesterone (Lutofolone) is used to cause menstrual periods in women who have not yet reached menopause but are not having periods due to a lack of Progesterone (Lutofolone) in the body. Progesterone (Lutofolone) is also used to prevent overgrowth in the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy.
    Progesterone (Lutofolone) should not be used to prevent heart disease or dementia, because Progesterone (Lutofolone) may actually increase your risk of developing these conditions.
    Progesterone (Lutofolone) may also be used for other purposes not listed in Progesterone (Lutofolone) guide.

    Progesterone (Lutofolone) side effects

    Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
    Stop using Progesterone (Lutofolone) and call your doctor at once if you have any of these serious side effects:
    • sudden numbness or weakness, especially on one side of the body;
    • sudden headache, confusion, pain behind the eyes, problems with vision, speech, or balance;
    • fast or pounding heartbeats;
    • chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
    • unusual or unexpected vaginal bleeding;
    • migraine headache;
    • nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
    • swelling in your hands, ankles, or feet;
    • fever, chills, body aches, flu symptoms;
    • a breast lump; or
    • symptoms of depression (sleep problems, weakness, mood changes).

    Less serious side effects may include:
    • mild nausea, diarrhea, bloating, stomach cramps;
    • dizziness, spinning sensation;
    • hot flashes;
    • mild headache;
    • joint pain;
    • breast pain or tenderness;
    • cough;
    • acne or increased hair growth;
    • changes in weight; or
    • vaginal itching, dryness, or discharge.

    This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
    See also: Side effects (in more detail)

    Progesterone (Lutofolone) dosing

    Usual Adult Dose for Amenorrhea:

    5 to 10 mg IM for six to eight consecutive days.
    400 mg orally for 10 days. Give dose in the evening.
    Secondary Amenorrhea:
    90 mg intravaginally, 4% gel, every other day for a total of six doses. If no response observed, the administration of the 8% gel every other day for a total of six doses may be used.

    Usual Adult Dose for Uterine Bleeding:

    5 to 10 mg IM daily for 6 doses.

    Usual Adult Dose for Endometrial Hyperplasia -- Prophylaxis:

    200 mg orally for 12 consecutive days, per 28 day cycle. Give dose in the evening.

    Usual Adult Dose for Progesterone Insufficiency:

    Assisted Reproductive Technology (ART) - Gel:
    90 mg of the 8% gel, once daily intravaginally, in women who require supplementation.
    90 mg of the 8% gel, twice daily intravaginally, in women with partial or complete ovarian failure who require replacement.
    If pregnancy occurs, therapy with the intravaginal gel may be continued until placental autonomy is achieved, up to 10 to 12 weeks.
    Assisted Reproductive Technology (ART) - Vaginal Insert
    100 mg administered vaginally two or three times daily starting at oocyte retrieval and continuing for up to 10 weeks total duration. Efficacy in women 35 years of age and older has not been clearly established. The appropriate dose in this age group has not been determined.
    Progesterone (Lutofolone) deficiency associated with menopause and perimenopause:
    Progesterone (Lutofolone) 1.7% topical cream: rub 1/4 to 1/2 teaspoon into the palms of the hands, soles of the feet, or other soft areas of skin once or twice daily.

    Usual Adult Dose for Premature Labor:

    Study - National Institute of Child Health and Human Development (NICHD) - Prevention of Recurrent Preterm Delivery in Women at High Risk: 17-alpha-hydroxyprogesterone caproate (17P) 250 mg IM once weekly starting on the 21st week of gestation through time of delivery or week 36 of gestation.
    Study (n=142) - Reduce Incidence of Spontaneous Preterm Birth in Women at Increased Risk: 100 mg vaginal suppository daily, between 24 and 34 weeks of gestation.

    Usual Adult Dose for Seizures:

    (Study=25) - Catamenial epilepsy [complex partial or secondary generalized motor seizures]:
    200 mg lozenge three times daily administered in relation to pattern of seizure exacerbation during luteal phase of menstrual cycle. For patients with perimenstrual exacerbation, dose was provided on day 23 through day 25 of menstrual cycle. For patients with seizure exacerbation during entire luteal phase, dose was provided on day 15 through day 25 of each menstrual cycle. The desired Progesterone (Lutofolone) serum level was between 5 and 25 ng/mL 4 hours after taking the lozenge. All patients continued taking their best antiseizure medication.

    Usual Adult Dose for Perimenopausal Symptoms:

    Progesterone deficiency associated with menopause and perimenopause:
    Progesterone (Lutofolone) 1.7% topical cream: Rub 1/4 to 1/2 teaspoonful into the palms of the hands, soles of feet, or other soft area once or twice daily.

    Select the most affordable brand or generic drug

    Generic drug is the basic drug with an active substance in it, and the name of the generic drug is same as active substance most of the times. Like Acetaminophen/Paracetemol is Generic name and it has different brand names like Tylenol, Acimol, Crocin, Calpol etc. All these Brand names contain the same Paracetemol, but the medications are manufactured by different companies, so the different brand names. Generic drug is always cheaper and affordable, and it can be replaced in place of brand name drug prescribed by the healthcare practitioner. The Generic medicine has same properties as branded medicine in terms of uses, indications, doses, side effects, so no need to worry on that. Just select the most affordable generic or branded medicine.

    StrengthQuantityPrice, USDCountry


    1. Dailymed."Progesterone: dailymed provides trustworthy information about marketed drugs in the united states. dailymed is the official provider of fda label information (package inserts).". (accessed August 28, 2018).
    2. Dailymed."Estradiol hemihydrate: dailymed provides trustworthy information about marketed drugs in the united states. dailymed is the official provider of fda label information (package inserts).". (accessed August 28, 2018).
    3. "Progesterone". (accessed August 28, 2018).

    Lutofolone - Frequently asked Questions

    Can Lutofolone be stopped immediately or do I have to stop the consumption gradually to ween off?

    In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.

    It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.

    How should I take Estradiol (Lutofolone)?

    Use Estradiol (Lutofolone) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

    • An extra patient leaflet is available with Estradiol (Lutofolone). Talk to your pharmacist if you have questions about this information.
    • To use, tear off a single applicator, separate the plastic wrap, and remove the applicator from the plastic wrap.
    • Select the position for vaginal insertion that is most comfortable for you (lying on the bed, squatting, or standing with one leg on a stool).
    • Place the finger of one hand on the applicator plunger. Use the other hand to gently and comfortably guide the applicator into the vagina. If the tablet falls out of the applicator before inserting the filled applicator, use a new applicator with a fresh tablet.
    • Insert the tablet as far into the vagina as it can comfortably go without force, or until half of the applicator is in your vagina, whichever is less.
    • After inserting the filled applicator, gently press the plunger until you hear a click and the plunger is fully depressed. This will eject the tablet inside your vagina. The tablet will dissolve slowly over several hours.
    • After depressing the plunger, gently remove the applicator and throw it away. Do not reuse the applicator.
    • You may use Estradiol (Lutofolone) at any time of the day. However, you should use it at the same time of day each time you use it.
    • Eating grapefruit or drinking grapefruit juice may increase the risk of estradiol's side effects. Talk to your doctor before including grapefruit or grapefruit juice in your diet while you are taking Estradiol (Lutofolone).
    • If you miss a dose of Estradiol (Lutofolone), use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

    Ask your health care provider any questions you may have about how to use Estradiol (Lutofolone).

    How should I take Progesterone (Lutofolone)?

    Use this medication exactly as it was prescribed for you. Do not use larger amounts, or use it for longer than recommended by your doctor. Follow the directions on your prescription label.

    Progesterone (Lutofolone) is sometimes given for only a short period of time, such as 6 to 12 days at a time during each menstrual cycle. Following your dosing schedule is very important for this medication to be effective. Try not to miss any doses.

    This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

    Take the pill form of Progesterone (Lutofolone) with a full glass of water.

    Apply Progesterone (Lutofolone) cream to the skin as directed by your doctor.

    Progesterone (Lutofolone) injection is given as a shot into a muscle. Your doctor, nurse, or other healthcare provider will give you this injection. You may be given instructions on how to use your injections at home. Do not use this medicine at home if you do not fully understand how to give the injection and properly dispose of needles and syringes used in giving the medicine.

    This medication can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are using Progesterone (Lutofolone).

    Your doctor will need to see you on a regular basis while you are using this medication. Do not miss any scheduled appointments.

    Store Progesterone (Lutofolone) at room temperature away from moisture, heat, and light.

    What other drugs will affect Progesterone (Lutofolone)?

    There may be other drugs that can interact with Progesterone (Lutofolone). Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

    Who should not take Progesterone (Lutofolone)?

    Some forms of this medication may contain peanut oil. Do not use Progesterone (Lutofolone) without telling your doctor if you have a peanut allergy.

    Do not use Progesterone (Lutofolone) if you have:

    • a history of breast cancer;

    • abnormal vaginal bleeding that a doctor has not checked;

    • liver disease;

    • if you are pregnant; or

    • if you have had a stroke, heart attack, or blood clot within the past year.

    If you have any of these other conditions, you may need a dose adjustment or special tests to safely use Progesterone (Lutofolone):

    • heart disease, circulation problems;

    • risk factors for coronary artery disease (such as smoking, being overweight, and having high blood pressure or high cholesterol);

    • migraines,

    • asthma;

    • kidney disease;

    • seizures or epilepsy;

    • a history of depression; or

    • diabetes.

    Do not use Progesterone (Lutofolone) without your doctor's consent if you are pregnant. Tell your doctor if you become pregnant during treatment. Use an effective form of birth control while you are using this medication.

    Progesterone (Lutofolone) can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

    Who should not take Estradiol (Lutofolone)?

    Some medical conditions may interact with Estradiol (Lutofolone). Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

    • if you are pregnant, planning to become pregnant, or are breast-feeding
    • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
    • if you have allergies to medicines, foods, or other substances
    • if you have a condition called hereditary angioedema
    • if you have a history of breast lumps, breast disease, or an abnormal mammogram, or if a member of your family has had breast cancer
    • if you have a vaginal infection or a history of uterus problems (eg, fibroids, endometriosis, abnormal vaginal bleeding, cancer), or you have had your uterus removed (hysterectomy)
    • if you have a history of asthma, depression, memory problems, diabetes, seizures, gallbladder disease, pancreatitis, heart problems, high blood cholesterol or triglyceride levels, high blood calcium levels, high blood pressure, low blood levels of parathyroid hormone, or porphyria
    • if you have a history of kidney or liver problems, yellowing of the skin or eyes, cancer, lupus, migraines, thyroid problems, or chorea (jerky, involuntary movements of the face, arms, or legs)
    • if you smoke, use tobacco, are very overweight, will be having surgery, or will be confined to a bed or chair for a period of time
    • if a member of your family has had high cholesterol or triglyceride levels, blood clots (eg, in the leg or lung), lupus, or has been very overweight

    Some MEDICINES MAY INTERACT with Estradiol (Lutofolone). Tell your health care provider if you are taking any other medicines, especially any of the following:

    • Azole antifungals (eg, ketoconazole), macrolide antibiotics (eg, erythromycin), or protease inhibitors (eg, ritonavir) because they may increase the risk of estradiol's side effects
    • Barbiturates (eg, phenobarbital), carbamazepine, hydantoins (eg, phenytoin), rifamycins (eg, rifampin), or St. John's wort because they may decrease estradiol's effectiveness
    • Thyroid hormones (eg, levothyroxine) because their effectiveness may be decreased by Estradiol (Lutofolone)

    This may not be a complete list of all interactions that may occur. Ask your health care provider if Estradiol (Lutofolone) may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

    Can Lutofolone be taken or consumed while pregnant?

    Please visit your doctor for a recommendation as such case requires special attention.

    Can Lutofolone be taken for nursing mothers or during breastfeeding?

    Kindly explain your state and condition to your doctor and seek medical advice from an expert.



    Following the study conducted by on Lutofolone, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Lutofolone. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.

    Patient reports

    Patient reported useful

    No survey data has been collected yet

    One patient reported side effects

    Does the Lutofolone Have Any Side Effects?
    Based on the survey report from users of, about No side effects number of people suffered some side effect after consumption of Lutofolone. All drugs have a portion of undesirable side effects. These effects could be irritations too insignificant for the patient to even notice. However, the side effects of drugs may be determined by several factors like severity of disease and conditions associated with individual patients. However, one of the biggest factors is the dosage consumed. The higher the quantity taken by an individual, the greater the healing effect and the corresponding side effect. All patients have their different intensity of side effects. Ensure you consult your health care provider immediately you notice an unusual side effect affect the consumption of Lutofolone.
    No side effects1

    Patient reported price estimates

    No survey data has been collected yet

    One patient reported frequency of use

    How often should I take Lutofolone?
    According to the survey, reported that users of Lutofolone should take Once in a day as the primarily recommended frequency. However, patients are advised to follow the dosage as prescribed by their physician religiously. To get the opinions of other patients on the ideal consumption frequency of the medicine, click here.
    Once in a day1

    One patient reported doses

    What is the specific doses you have used?
    Lutofolone May come in various doses. In most cases, antibiotics, antihypertensive, pain killers and anti-diabetic drugs available in different doses. Your doctor may prescribe any of the doses based on the severity of the patient's condition. According to our reports, users of used the drugs in the following dosage percentage (Provide dosage percentage). Only a handful of drugs are made in a single or fixed dose. Regular health conditions like fever have similar doses. For instance [acetaminophen, 500mg] was used by the patients surveyed although it comes in different doses.

    Patient reported time for results

    No survey data has been collected yet

    One patient reported administration

    When is the best condition to take Lutofolone: Before or after food?
    Based on the survey, the users of voted that Lutofolone is best taken at Empty stomach. It is however worthy of mention that this popular vote may not be an appropriate description for your particular health condition. See your doctor for professional medical advice as regards the best time to take this medicine. If you wish to see the views of other users on the best time to take the medicine, simply click here.
    Empty stomach1

    Two patients reported age


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    The information was verified by Dr. Harshad Shah, MD Pharmacology