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What is Lextone

Lextone is a female hormone important for the regulation of ovulation and menstruation.
Lextone is used to cause menstrual periods in women who have not yet reached menopause but are not having periods due to a lack of Lextone in the body. Lextone is also used to prevent overgrowth in the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy.
Lextone should not be used to prevent heart disease or dementia, because Lextone may actually increase your risk of developing these conditions.
Lextone may also be used for other purposes not listed in Lextone guide.

Lextone side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using Lextone and call your doctor at once if you have any of these serious side effects:

Less serious side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
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Lextone dosing

Usual Adult Dose for Amenorrhea:

5 to 10 mg IM for six to eight consecutive days.
400 mg orally for 10 days. Give dose in the evening.
Secondary Amenorrhea:
90 mg intravaginally, 4% gel, every other day for a total of six doses. If no response observed, the administration of the 8% gel every other day for a total of six doses may be used.

Usual Adult Dose for Uterine Bleeding:

5 to 10 mg IM daily for 6 doses.

Usual Adult Dose for Endometrial Hyperplasia -- Prophylaxis:

200 mg orally for 12 consecutive days, per 28 day cycle. Give dose in the evening.

Usual Adult Dose for Lextone Insufficiency:

Assisted Reproductive Technology - Gel:
90 mg of the 8% gel, once daily intravaginally, in women who require supplementation.
90 mg of the 8% gel, twice daily intravaginally, in women with partial or complete ovarian failure who require replacement.
If pregnancy occurs, therapy with the intravaginal gel may be continued until placental autonomy is achieved, up to 10 to 12 weeks.
Assisted Reproductive Technology (ART) - Vaginal Insert
100 mg administered vaginally two or three times daily starting at oocyte retrieval and continuing for up to 10 weeks total duration. Efficacy in women 35 years of age and older has not been clearly established. The appropriate dose in this age group has not been determined.
Lextone deficiency associated with menopause and perimenopause:
Lextone 1.7% topical cream: rub 1/4 to 1/2 teaspoon into the palms of the hands, soles of the feet, or other soft areas of skin once or twice daily.

Usual Adult Dose for Premature Labor:

Study (n=459) - National Institute of Child Health and Human Development (NICHD) - Prevention of Recurrent Preterm Delivery in Women at High Risk: 17-alpha-hydroxyprogesterone caproate (17P) 250 mg IM once weekly starting on the 21st week of gestation through time of delivery or week 36 of gestation.
Study (n=142) - Reduce Incidence of Spontaneous Preterm Birth in Women at Increased Risk: 100 mg vaginal suppository daily, between 24 and 34 weeks of gestation.

Usual Adult Dose for Seizures:

- Catamenial epilepsy [complex partial or secondary generalized motor seizures]:
200 mg lozenge three times daily administered in relation to pattern of seizure exacerbation during luteal phase of menstrual cycle. For patients with perimenstrual exacerbation, dose was provided on day 23 through day 25 of menstrual cycle. For patients with seizure exacerbation during entire luteal phase, dose was provided on day 15 through day 25 of each menstrual cycle. The desired Lextone serum level was between 5 and 25 ng/mL 4 hours after taking the lozenge. All patients continued taking their best antiseizure medication.

Usual Adult Dose for Perimenopausal Symptoms:

Lextone deficiency associated with menopause and perimenopause:
Lextone 1.7% topical cream: Rub 1/4 to 1/2 teaspoonful into the palms of the hands, soles of feet, or other soft area once or twice daily.

Select the most affordable brand or generic drug


StrengthQuantityPrice, USDCountry
CYGEST 100 MG CAPSULE 1 strip(s) (10 capsules each) $1.75Inga Laboratories Pvt Ltd
Cygest 200mg SG-CAP / 10 $2.55
Cygest 100 mg Capsule $0.14
Cygest 400 mg x 15's $22.20
200 mg x 10's $2.72
100 mg x 1's $0.84
200 mg x 1's $1.32
100 mg10 Tablet$1.37
100 mg10 Tablet$1.39
EVAGEST inj 50 mg x 1 mL x 4ml $1.53Olcare (Evacare)
200 mg x 10's $2.51
EVAGEST tab 200 mg x 10's $2.51Olcare (Evacare)
Evagest 200mg TAB / 10 $2.51
EVAGEST Capsule/ Tablet / 200mg (10 units) $2.51Olcare (Evacare Division)
100 mg x 10's $1.39
EVAGEST tab 100 mg x 10's $1.39Olcare (Evacare)
Evagest 100mg TAB / 10 $1.39
EVAGEST Capsule/ Tablet / 100mg (10 units) $1.39Olcare (Evacare Division)
HILGESTRONE cap 200 mg x 10's $2.39HLL Lifecare
Hilgestrone 200mg CAP / 10 $2.39
Hilgestrone 200mg Injection $0.66Hindustan Latex Ltd
HILGESTRONE 100 MG CAPSULE 1 strip(s) (10 capsules each) $1.26Hindustan Latex Ltd
HILGESTRONE cap 100 mg x 10's $1.26HLL Lifecare
Hilgestrone 100mg CAP / 10 $1.26
HILGESTRONE 200 MG INJECTION 1 vial(s) (2 ML injection each) $1.32Hindustan Latex Ltd
100 mg10 Capsule$1.40
Hormorin 100 mg Tablet $0.14
Hormorin 100mg Capsule $0.23Torrent Pharmaceuticals Ltd
HORMORIN 100MG CAPSULE 1 strip(s) (10 capsules each) $2.33Torrent Pharmaceuticals Ltd
Hormorin 200 mg Tablet $0.27
Hormorin 200mg Capsule $0.43Torrent Pharmaceuticals Ltd
HORMORIN 200MG CAPSULE 1 strip(s) (10 capsules each) $4.33Torrent Pharmaceuticals Ltd
Macgest 100mg Capsule $0.21Macleods Pharmaceuticals Pvt Ltd
MACGEST cap 200 mg x 10's $3.12Macleods (Osteva)
Macgest 300mg Tablet SR $0.52Macleods Pharmaceuticals Pvt Ltd
Macgest 100mg CAP / 10 $1.29
200 mg x 10's $1.95
N-SANIGEST cap 200 mg x 10's $2.73Sanify (Syntonic)
N-Sanigest 200mg CAP / 10 $2.73
100 mg x 10's $1.05
N-SANIGEST cap 100 mg x 10's $1.05Sanify (Syntonic)
N-Sanigest 100mg CAP / 10 $1.05
NATUROGEST Capsule/ Tablet / 100mg (10 units) $1.72Zydus Cadila (German Remedies Division)
NATUROGEST inj 200 mg x 2 mL x 2ml $2.23Zydus (G.Rem)
NATUROGEST Capsule/ Tablet / 400mg (6 units) $3.23Zydus Cadila (German Remedies Division)
Naturogest 200mg Tablet SR $0.46German Remedies
NATUROGEST SR 300 MG TABLET 1 strip(s) (10 tablets each) $5.60Zydus Cadila
NATUROGEST AQ 25MG INJECTION 1 vial(s) (1 ML injection each) $0.84Zydus Cadila
Naturogest 100mg Injection $1.26German Remedies
NoStrengthProvided60 $51.00Australia, Canada, NZ, Singapore, UK
200 mg x 10's $2.69
PREGCITIL soft-gelatin cap 200 mg x 10's $2.69Molekule
Pregcitil 200mg SG-CAP / 10 $2.69
Pregcitil 200mg Capsule $0.30Molekule India Pvt Ltd
PREGCITIL 200 MG CAPSULE 1 strip(s) (10 capsules each) $2.96Molekule India Pvt Ltd
Pregcitil 100mg Capsule $0.14Molekule India Pvt Ltd
100 mg x 10's $1.39
PREGCITIL 100 MG CAPSULE 1 strip(s) (10 capsules each) $1.39Molekule India Pvt Ltd
PREGCITIL soft-gelatin cap 100 mg x 10's $1.39Molekule
Pregcitil 100mg SG-CAP / 10 $1.39
40 mg10 $0.42
Prid 20mg TAB / 100 $2.16
PRID tab 5 mg x 10's $0.06Samarth
PRID tab 10 mg x 10's $0.11Samarth
200 mg10 Tablet$2.10
200 mg x 1's $1.68
PROZY inj 200 mg x 2ml $1.68Neiss
Prozy 200mg INJ / 1 $1.68
10 's $2.52
PROZY softgel 200 mg x 10's $2.52Neiss
Prozy - SG-CAP / 10 $2.52
PUREGEST soft-gelatin cap 200 mg x 10's $2.51Sun
PUREGEST 100 MG CAPSULE 1 strip(s) (10 capsules each) $3.22Sun Pharma Laboratories Ltd
Puregest 100mg Injection $0.58Sun Pharmaceutical Industries Ltd
PUREGEST soft-gelatin cap 100 mg x 10's $1.36Sun
200 mg x 1's $1.51
Rigest 200mg INJ / 1 $1.51
100 mg x 10's $1.53
Rigest 100mg SG-CAP / 10 $1.53
200 mg x 10's $2.79
Rigest 200mg SG-CAP / 10 $2.79
100 mg x 1's $0.95
Rigest 100mg INJ / 1 $0.95
Susten 100mg Injection $1.44Sun Pharmaceutical Industries Ltd
SUSTEN soft-gelatin cap 100 mg x 10's $1.51Sun
Susten 50mg/mL AMP / 4ml $2.18
Susten 200mg SG-CAP / 10 $2.69
SUSTEN SR 200 MG TABLET 1 strip(s) (10 tablets each) $3.99Sun Pharma Laboratories Ltd
Susten 200mg Tablet SR $0.44Sun Pharmaceutical Industries Ltd
Susten 300mg Soft Gelatin Capsule $4.87Sun Pharmaceutical Industries Ltd
SUSTEN soft-gelatin cap 400 mg x 10's $5.67Sun
SUSTEN Injection / 50mg (1 units) $0.63Sun Pharmaceuticals (Spectra Division)
Susten 8% GEL / 1 $0.98
SUSTEN vag gel 8 % w/w x 1.35g $1.18Sun
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References

  1. Dailymed."Progesterone: dailymed provides trustworthy information about marketed drugs in the united states. dailymed is the official provider of fda label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
  2. "Progesterone". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
  3. "Progesterone". http://www.drugbank.ca/drugs/DB0039... (accessed August 28, 2018).

Lextone - Frequently asked Questions

Can Lextone be stopped immediately or do I have to stop the consumption gradually to ween off?

In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.

It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.

Who should not take Lextone?

Some forms of this medication may contain peanut oil. Do not use Lextone without telling your doctor if you have a peanut allergy.

Do not use Lextone if you have:

If you have any of these other conditions, you may need a dose adjustment or special tests to safely use Lextone:

Do not use Lextone without your doctor's consent if you are pregnant. Tell your doctor if you become pregnant during treatment. Use an effective form of birth control while you are using this medication.

Lextone can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

What other drugs will affect Lextone?

There may be other drugs that can interact with Lextone. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

How should I take Lextone?

Use this medication exactly as it was prescribed for you. Do not use larger amounts, or use it for longer than recommended by your doctor. Follow the directions on your prescription label.

Lextone is sometimes given for only a short period of time, such as 6 to 12 days at a time during each menstrual cycle. Following your dosing schedule is very important for this medication to be effective. Try not to miss any doses.

This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

Take the pill form of Lextone with a full glass of water.

Apply Lextone cream to the skin as directed by your doctor.

Lextone injection is given as a shot into a muscle. Your doctor, nurse, or other healthcare provider will give you this injection. You may be given instructions on how to use your injections at home. Do not use this medicine at home if you do not fully understand how to give the injection and properly dispose of needles and syringes used in giving the medicine.

This medication can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are using Lextone.

Your doctor will need to see you on a regular basis while you are using this medication. Do not miss any scheduled appointments.

Store Lextone at room temperature away from moisture, heat, and light.

Can Lextone be taken or consumed while pregnant?

Please visit your doctor for a recommendation as such case requires special attention.

Can Lextone be taken for nursing mothers or during breastfeeding?

Kindly explain your state and condition to your doctor and seek medical advice from an expert.

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Reviews

Following the study conducted by gmedication.com on Lextone, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Lextone. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.

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The information was verified by Dr. Vishal Pawar, MD Pharmacology