Treating rheumatoid arthritis by reducing signs and symptoms, improving physical function, and preventing the development of structural damage to the joints. Leflunomida Stada is a pyrimidine synthesis inhibitor. It is thought to work by blocking certain enzymes responsible for abnormal tissue development or growth.
Important safety information:
Leflunomida Stada may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Leflunomida Stada with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Drinking alcohol while you are taking Leflunomida Stada may increase the risk of liver problems. Talk with your doctor before drinking alcohol while taking Leflunomida Stada.
Leflunomida Stada may reduce the number of clot-forming cells in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.
Leflunomida Stada may lower the ability of your body to fight infection. Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills.
Do not receive a live vaccine (eg, measles, mumps) while you are taking Leflunomida Stada. Talk with your doctor before you receive any vaccine.
The safety of Leflunomida Stada in patients with inactive TB has not been confirmed. You may need to have a TB skin test before you start Leflunomida Stada to determine if you have TB infection. Discuss any questions or concerns with your doctor.
Serious and sometimes fatal liver problems have been reported with Leflunomida Stada. Contact your doctor right away if you develop symptoms such as dark urine, pale stools, yellowing of the skin or eyes, stomach pain, severe or persistent nausea or loss of appetite, or unusual tiredness.
A serious and sometimes fatal lung problem (interstitial lung disease) has been reported with Leflunomida Stada. Contact your doctor right away if you develop new or worsening breathing problems, such as cough or shortness of breath (with or without fever).
Serious and sometimes fatal skin reactions (eg, Stevens-Johnson syndrome, toxic epidermal necrolysis) have been rarely reported with Leflunomida Stada. Contact your doctor right away if you develop a rash; red, swollen, blistered, or peeling skin; or blisters on the inside of the eyes, nose, or mouth.
Lab tests, including liver function, blood pressure, and complete blood cell counts, may be performed to monitor your progress or check for side effects. Be sure to keep all doctor and lab appointments.
Use Leflunomida Stada with caution in the ELDERLY; they may be more likely to develop burning, numbness, or tingling.
Leflunomida Stada may remain in the body for 2 years or longer after you stop taking it. Your doctor may prescribe medicine to help remove Leflunomida Stada from your body more quickly after you finish treatment (drug elimination procedure). Talk with your doctor for more information.
The risk of harm or death to a fetus fathered by a man using Leflunomida Stada is not known. Men who take Leflunomida Stada should talk with their doctor about the need to use a condom when having sex with a woman who may become pregnant. If you wish to father a child, talk with your doctor. You may need to stop Leflunomida Stada and complete the drug elimination procedure to remove it from your blood before you father a child.
If you are able to become pregnant, you must not start Leflunomida Stada unless it has been confirmed that you are not pregnant. You will need to use an effective form of birth control while you take Leflunomida Stada and for as long as Leflunomida Stada remains in your body. If you plan to become pregnant, talk with your doctor about stopping Leflunomida Stada and completing the drug elimination procedure before you become pregnant. Talk with your doctor for more information or if you have questions about effective birth control.
PREGNANCY and BREAST-FEEDING: Do not use Leflunomida Stada if you are pregnant. It may cause birth defects or fetal death. You must have a negative pregnancy test before you start treatment with Leflunomida Stada. Do not become pregnant while you are taking it. Contact your doctor at once if your period does not occur when expected or if you suspect that you are pregnant. It is not known if Leflunomida Stada is found in breast milk. Do not breast-feed while taking Leflunomida Stada.
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Leflunomida Stada side effects
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blisters on the inside of the eyes, nose, or mouth; burning, numbness, or tingling; chest pain; fast or irregular heartbeat; muscle cramps, including leg cramps; new or worsening breathing problems (eg, cough or shortness of breath, with or without fever); red, swollen, blistered, or peeling skin; severe or persistent vomiting; symptoms of high blood pressure (eg, severe or persistent headache or dizziness, vision changes); symptoms of infection (eg, fever, chills, sore throat, cough, increased or painful urination); symptoms of liver problems (eg, dark urine, pale stools, yellowing of the skin or eyes, stomach pain, severe or persistent nausea or loss of appetite); unusual or easy bruising or bleeding; unusual tiredness; unusually pale skin.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
Dailymed."Leflunomide: dailymed provides trustworthy information about marketed drugs in the united states. dailymed is the official provider of fda label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
Can Leflunomida Stada be stopped immediately or do I have to stop the consumption gradually to ween off?
In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.
It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.
Who should not take Leflunomida Stada?
Some medical conditions may interact with Leflunomida Stada. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have a weakened immune system, an infection, a history of an infection that keeps coming back, or you have recently received a vaccination
if you have a history of lung problems, tuberculosis (TB) or a positive TB test, high blood pressure, blood or bone marrow problems, diabetes, liver problems, or abnormal liver function tests, or if you drink alcoholic beverages
if you have or have a history of kidney problems or you are on dialysis
if you take or have recently taken methotrexate, another medicine to treat rheumatoid arthritis, or another medicine that may suppress your immune system
if you are taking medicine to treat or prevent malaria
Some MEDICINES MAY INTERACT with Leflunomida Stada. Tell your health care provider if you are taking any other medicines, especially any of the following:
Methotrexate because the risk of liver problems, blood problems, or infection may be increased
Rifampin or teriflunomide because they may increase the risk of leflunomide's side effects
Anticoagulants (eg, warfarin) because the risk of its side effects, including bleeding, may be increased by Leflunomida Stada
Medicines that may suppress the immune system because the risk of infection or unusual bruising or bleeding may be increased. Ask your doctor if you are unsure if any of your medicines may suppress the immune system
Medicines that may cause nerve problems, because the risk of a certain nerve side effect (burning, numbness, or tingling sensation) may be increased. Ask your doctor if you are unsure if any of you medicines may cause nerve problems
Cholestyramine because it may decrease leflunomide's effectiveness
Medicines that may harm the liver (eg, acetaminophen, methotrexate, ketoconazole, isoniazid, certain medicines for HIV infection) because the risk of liver side effects may be increased. Ask your doctor if you are unsure if any of your medicines might harm the liver
This may not be a complete list of all interactions that may occur. Ask your health care provider if Leflunomida Stada may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How should I take Leflunomida Stada?
Use Leflunomida Stada as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Take Leflunomida Stada by mouth with or without food.
It may take 4 weeks or more to notice any improvement while taking Leflunomida Stada.
If you miss a dose of Leflunomida Stada, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Leflunomida Stada.
Can Leflunomida Stada be taken or consumed while pregnant?
Please visit your doctor for a recommendation as such case requires special attention.
Can Leflunomida Stada be taken for nursing mothers or during breastfeeding?
Kindly explain your state and condition to your doctor and seek medical advice from an expert.
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Reviews
Following the study conducted by gmedication.com on Leflunomida Stada, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Leflunomida Stada. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.
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