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What is Hystrogest

Hystrogest is a female hormone important for the regulation of ovulation and menstruation.
Hystrogest is used to cause menstrual periods in women who have not yet reached menopause but are not having periods due to a lack of Hystrogest in the body. Hystrogest is also used to prevent overgrowth in the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy.
Hystrogest should not be used to prevent heart disease or dementia, because Hystrogest may actually increase your risk of developing these conditions.
Hystrogest may also be used for other purposes not listed in Hystrogest guide.

Hystrogest side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using Hystrogest and call your doctor at once if you have any of these serious side effects:

Less serious side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
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Hystrogest dosing

Usual Adult Dose for Amenorrhea:

5 to 10 mg IM for six to eight consecutive days.
400 mg orally for 10 days. Give dose in the evening.
Secondary Amenorrhea:
90 mg intravaginally, 4% gel, every other day for a total of six doses. If no response observed, the administration of the 8% gel every other day for a total of six doses may be used.

Usual Adult Dose for Uterine Bleeding:

5 to 10 mg IM daily for 6 doses.

Usual Adult Dose for Endometrial Hyperplasia -- Prophylaxis:

200 mg orally for 12 consecutive days, per 28 day cycle. Give dose in the evening.

Usual Adult Dose for Hystrogest Insufficiency:

Assisted Reproductive Technology - Gel:
90 mg of the 8% gel, once daily intravaginally, in women who require supplementation.
90 mg of the 8% gel, twice daily intravaginally, in women with partial or complete ovarian failure who require replacement.
If pregnancy occurs, therapy with the intravaginal gel may be continued until placental autonomy is achieved, up to 10 to 12 weeks.
Assisted Reproductive Technology (ART) - Vaginal Insert
100 mg administered vaginally two or three times daily starting at oocyte retrieval and continuing for up to 10 weeks total duration. Efficacy in women 35 years of age and older has not been clearly established. The appropriate dose in this age group has not been determined.
Hystrogest deficiency associated with menopause and perimenopause:
Hystrogest 1.7% topical cream: rub 1/4 to 1/2 teaspoon into the palms of the hands, soles of the feet, or other soft areas of skin once or twice daily.

Usual Adult Dose for Premature Labor:

Study (n=459) - National Institute of Child Health and Human Development (NICHD) - Prevention of Recurrent Preterm Delivery in Women at High Risk: 17-alpha-hydroxyprogesterone caproate (17P) 250 mg IM once weekly starting on the 21st week of gestation through time of delivery or week 36 of gestation.
Study (n=142) - Reduce Incidence of Spontaneous Preterm Birth in Women at Increased Risk: 100 mg vaginal suppository daily, between 24 and 34 weeks of gestation.

Usual Adult Dose for Seizures:

- Catamenial epilepsy [complex partial or secondary generalized motor seizures]:
200 mg lozenge three times daily administered in relation to pattern of seizure exacerbation during luteal phase of menstrual cycle. For patients with perimenstrual exacerbation, dose was provided on day 23 through day 25 of menstrual cycle. For patients with seizure exacerbation during entire luteal phase, dose was provided on day 15 through day 25 of each menstrual cycle. The desired Hystrogest serum level was between 5 and 25 ng/mL 4 hours after taking the lozenge. All patients continued taking their best antiseizure medication.

Usual Adult Dose for Perimenopausal Symptoms:

Hystrogest deficiency associated with menopause and perimenopause:
Hystrogest 1.7% topical cream: Rub 1/4 to 1/2 teaspoonful into the palms of the hands, soles of feet, or other soft area once or twice daily.

Select the most affordable brand or generic drug


StrengthQuantityPrice, USDCountry
Belgest 100 mg Capsule $0.15
BELGEST softgel 100 mg x 10's $1.46Blubell
100 mg x 100's $14.56
Belgest Natural MicronisedProgesterone 100mg SOFTGEL / 100 $14.56
Belgest 200 mg Capsule $0.27
BELGEST softgel 200 mg x 10's $2.72Blubell
200 mg x 100's $27.23
Belgest Natural MicronisedProgesterone 200mg SOFTGEL / 100 $27.23
200 mg x 2 mL x 1's $1.71
Celogest 200mg S-GEL / 10 $2.31
Celogest 200 mg Injection $0.85
100 mg x 10's $1.34
8 %gel15 applicators$74.00Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
8 %gel45 applicators$173.00Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
8 %gel45 applicators$174.00Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
8 %gel90 applicators$323.00Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
8 % x 1's $2.20
Crinone NA Tablet $2.20Serum Institute Of India Ltd
Crinone 8% GEL / 1 $2.20
CRINONE vag gel 8 % x 1.125g $2.31MSPL
Crinone 8 % x 15's $107.92
Crinone 8 % x 90 mg x 15's $83.35
E-GESTS inj 50 mg x 1 mL x 4ml $1.53Olcare (Evacare)
E-GESTS softgel 100 mg x 10's $1.89Olcare (Evacare)
E-GESTS softgel 200 mg x 10's $3.77Olcare (Evacare)
E-GESTS inj 50 mg x 1 mL x 2ml $1.04Olcare (Evacare)
200 mg x 1 mL x 4ml $2.03
Ets 200mg CAP / 10 $2.66
ETS inj 100 mg x 1 mL x 2ml $1.05Emcure (Shweiz)
Fulgest 100mg (Micronised naturalprogesterone) SG-CAP / 10 $1.40
200 mg x 10's $2.24
Fulgest 200mg Capsule SR $0.40Micro Labs Ltd
GES-ONE soft-gelatin cap 100 mg x 10's $1.40Rass HC
Ges-One 200mg AMP / 4ml $1.68
GES-ONE inj 100 mg x 2ml $0.97Rass HC
100 mg10 Tablet$1.40
Gester NP 100 mg Tablet $0.14
Gester NP 200 mg Tablet $0.28
50 mg/ml30 ml$308.61Barbados, Canada, NZ, UK
100 mg x 10's $1.47
GESTONE 8% GEL 1 tube(s) (20 GM gel each) $2.06Ferring Pharmaceuticals
GESTONE Capsule/ Tablet / 200mg (10 units) $2.59Ferring Pharmaceuticals
50 mg x 1 mL x 1ml $0.63
GESTONE 400 MG CAPSULE 1 strip(s) (10 capsules each) $6.32Ferring Pharmaceuticals
Gestone 100mg AMP / 2ml $1.05
100 mg10 Capsule$1.05
N-GEST softgel 200 mg x 10's $2.37Elmex
N-Gest Natural micronisedProgesterone 200mg S-GEL / 10 $2.37
200 mg10 Tablet$2.80
NAM 100MG TABLET 1 strip(s) (10 tablets each) $0.20Lincoln Pharmaceuticals Ltd
Nam 100mg Suspension $0.26Lincoln Pharmaceuticals Ltd
Nam 200mg TAB / 10 $0.42
NATURONE 200MG INJECTION 1 vial(s) (4 ML injection each) $2.00Scott Edil Pharmacia Ltd
Naturone 100mg Injection $0.52Scott Edil Pharmacia Ltd
200 mg10 Tablet$2.52
200 mg x 2ml $1.96
PREGLON inj 200 mg x 2ml $1.96Novaduo
Preglon 200mg AMP / 2ml $1.96
200 mg x 10's $2.52
PREGLON tab 200 mg x 10's $2.52Novaduo
Preglon 200mg TAB / 10 $2.52
100 mg x 10's $1.39
PREGLON tab 100 mg x 10's $1.39Novaduo
Preglon 100mg TAB / 10 $1.39
Progesteron 1%/1ml - 5 Vial $10.40
Progesteron 2.5%/1ml - 5 Vial $14.60
Progesteron 25mg/1ml - 5 Vial $15.60
Progesteron 1%/1ml - 10 Vial $16.70
50 mg/ml10 ml$102.87Barbados, Canada, NZ, UK
100 mg10 Capsule$1.33
200 mg x 10's $2.09
PROGEZ soft-gelatin cap 200 mg x 10's $2.09Ritz Pharma
Progez 200mg SG-CAP / 10 $2.09
Progez 200mg Capsule $0.26Ritz Pharma
PROGEZ 200MG CAPSULE 1 strip(s) (10 capsules each) $2.56Ritz Pharma
100 mg x 10's $1.33
PROGEZ soft-gelatin cap 100 mg x 10's $1.33Ritz Pharma
Progez 100mg SG-CAP / 10 $1.33
Pyrtex 200mg VIAL / 1 $1.79
PYRTEX inj 100 mg x 2ml $0.95Scoshia
100 mg10 Capsule$1.39
SUGEST Capsule/ Tablet / 100mg (10 units) $1.57Uni - Sankyo
SUGEST tab 200 mg x 10's $2.10Uni Sankyo
Sugest 200mg Capsule $0.26Sanzyme Ltd
Sugest 200mg Soft Gelatin Capsule $4.19Sanzyme Ltd
Sugest 200mg Injection $0.93Sanzyme Ltd
SUGEST soft-gelatin cap 100 mg x 10's $1.22Uni Sankyo
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References

  1. Dailymed."Progesterone: dailymed provides trustworthy information about marketed drugs in the united states. dailymed is the official provider of fda label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
  2. "Progesterone". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
  3. "Progesterone". http://www.drugbank.ca/drugs/DB0039... (accessed August 28, 2018).

Hystrogest - Frequently asked Questions

Can Hystrogest be stopped immediately or do I have to stop the consumption gradually to ween off?

In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.

It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.

What other drugs will affect Hystrogest?

There may be other drugs that can interact with Hystrogest. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Who should not take Hystrogest?

Some forms of this medication may contain peanut oil. Do not use Hystrogest without telling your doctor if you have a peanut allergy.

Do not use Hystrogest if you have:

If you have any of these other conditions, you may need a dose adjustment or special tests to safely use Hystrogest:

Do not use Hystrogest without your doctor's consent if you are pregnant. Tell your doctor if you become pregnant during treatment. Use an effective form of birth control while you are using this medication.

Hystrogest can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take Hystrogest?

Use this medication exactly as it was prescribed for you. Do not use larger amounts, or use it for longer than recommended by your doctor. Follow the directions on your prescription label.

Hystrogest is sometimes given for only a short period of time, such as 6 to 12 days at a time during each menstrual cycle. Following your dosing schedule is very important for this medication to be effective. Try not to miss any doses.

This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

Take the pill form of Hystrogest with a full glass of water.

Apply Hystrogest cream to the skin as directed by your doctor.

Hystrogest injection is given as a shot into a muscle. Your doctor, nurse, or other healthcare provider will give you this injection. You may be given instructions on how to use your injections at home. Do not use this medicine at home if you do not fully understand how to give the injection and properly dispose of needles and syringes used in giving the medicine.

This medication can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are using Hystrogest.

Your doctor will need to see you on a regular basis while you are using this medication. Do not miss any scheduled appointments.

Store Hystrogest at room temperature away from moisture, heat, and light.

Can Hystrogest be taken or consumed while pregnant?

Please visit your doctor for a recommendation as such case requires special attention.

Can Hystrogest be taken for nursing mothers or during breastfeeding?

Kindly explain your state and condition to your doctor and seek medical advice from an expert.

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Reviews

Following the study conducted by gmedication.com on Hystrogest, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Hystrogest. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.

Patient reports

Patient reported useful

No survey data has been collected yet


Patient reported side effects

No survey data has been collected yet


Patient reported price estimates

No survey data has been collected yet


One patient reported frequency of use

How often should I take Hystrogest?
According to the survey, gmedication.com reported that users of Hystrogest should take Twice in a day as the primarily recommended frequency. However, patients are advised to follow the dosage as prescribed by their physician religiously. To get the opinions of other patients on the ideal consumption frequency of the medicine, click here.
Patients%
Twice in a day1
100.0%


One patient reported doses

What is the specific doses you have used?
Hystrogest May come in various doses. In most cases, antibiotics, antihypertensive, pain killers and anti-diabetic drugs available in different doses. Your doctor may prescribe any of the doses based on the severity of the patient's condition. According to our reports, users of gmedication.com used the drugs in the following dosage percentage (Provide dosage percentage). Only a handful of drugs are made in a single or fixed dose. Regular health conditions like fever have similar doses. For instance [acetaminophen, 500mg] was used by the patients surveyed although it comes in different doses.
Patients%
101-200mg1
100.0%


One patient reported time for results

How long will I use Hystrogest before I begin to notice the effect?
According to the report by users of gmedication.com, about 2 weeks and a few days was the most common time duration among the participants, before they began to feel relief in their health conditions. It is noteworthy that you may not get the same result with other users within the same time frame. Several factors determine the timeframe; hence we implore you to consult your medical expert to get professional advice on how long you should expect to see improvement while consuming Hystrogest. However, if you wish to get the response of other users on the time effectiveness of using Hystrogest kindly click here
Patients%
2 weeks1
100.0%


Patient reported administration

No survey data has been collected yet


Patient reported age

No survey data has been collected yet


Patient reviews


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The information was verified by Dr. Vishal Pawar, MD Pharmacology