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consists of Estradiol, Progesterone.

Estradiol (Hosterona)

What is Estradiol (Hosterona)

Treating itching, burning, and dryness in or around the vaginal area in women past menopause.
Estradiol (Hosterona) is a vaginal estrogen tablet. It works by increasing the amount of estrogen in the body in certain women who do not produce enough on their own.

Important safety information:

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Estradiol (Hosterona) side effects

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
  • Breast pain or tenderness; diarrhea; hair loss; headache; mild fluid retention; mild nausea or vomiting; spotting or breakthrough bleeding; stomach cramps or bloating.
  • Seek medical attention right away if any of these SEVERE side effects occur:
  • Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); abnormal vaginal bleeding; breast lumps or pain; bulging eyes; calf pain, swelling, or tenderness; chest pain; coughing up blood; fainting; mental or mood changes (eg, depression); migraine headache; new or worsening memory problems; new or worsening vaginal pain or irritation; pelvic pain; severe or persistent dizziness or headache; severe or persistent stomach or back pain (with or without nausea or vomiting); shortness of breath; swelling of the hands or feet; symptoms of heart attack (eg, chest, jaw, or arm pain; sudden, severe nausea or vomiting; shortness of breath; sudden, unusual sweating); symptoms of liver problems (eg, dark urine, pale stools, yellowing of the skin or eyes); symptoms of stroke (eg, one-sided weakness, slurred speech, confusion); unusual vaginal discharge/itching/odor; vision loss or other vision changes; vomiting.

  • This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

    Progesterone (Hosterona)

    What is Progesterone (Hosterona)

    Progesterone (Hosterona) is a female hormone important for the regulation of ovulation and menstruation.
    Progesterone (Hosterona) is used to cause menstrual periods in women who have not yet reached menopause but are not having periods due to a lack of Progesterone (Hosterona) in the body. Progesterone (Hosterona) is also used to prevent overgrowth in the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy.
    Progesterone (Hosterona) should not be used to prevent heart disease or dementia, because Progesterone (Hosterona) may actually increase your risk of developing these conditions.
    Progesterone (Hosterona) may also be used for other purposes not listed in Progesterone (Hosterona) guide.

    Progesterone (Hosterona) side effects

    Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
    Stop using Progesterone (Hosterona) and call your doctor at once if you have any of these serious side effects:

    Less serious side effects may include:

    This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
    See also: Side effects (in more detail)
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    Progesterone (Hosterona) dosing

    Usual Adult Dose for Amenorrhea:

    5 to 10 mg IM for six to eight consecutive days.
    400 mg orally for 10 days. Give dose in the evening.
    Secondary Amenorrhea:
    90 mg intravaginally, 4% gel, every other day for a total of six doses. If no response observed, the administration of the 8% gel every other day for a total of six doses may be used.

    Usual Adult Dose for Uterine Bleeding:

    5 to 10 mg IM daily for 6 doses.

    Usual Adult Dose for Endometrial Hyperplasia -- Prophylaxis:

    200 mg orally for 12 consecutive days, per 28 day cycle. Give dose in the evening.

    Usual Adult Dose for Progesterone Insufficiency:

    Assisted Reproductive Technology (ART) - Gel:
    90 mg of the 8% gel, once daily intravaginally, in women who require supplementation.
    90 mg of the 8% gel, twice daily intravaginally, in women with partial or complete ovarian failure who require replacement.
    If pregnancy occurs, therapy with the intravaginal gel may be continued until placental autonomy is achieved, up to 10 to 12 weeks.
    Assisted Reproductive Technology (ART) - Vaginal Insert
    100 mg administered vaginally two or three times daily starting at oocyte retrieval and continuing for up to 10 weeks total duration. Efficacy in women 35 years of age and older has not been clearly established. The appropriate dose in this age group has not been determined.
    Progesterone (Hosterona) deficiency associated with menopause and perimenopause:
    Progesterone (Hosterona) 1.7% topical cream: rub 1/4 to 1/2 teaspoon into the palms of the hands, soles of the feet, or other soft areas of skin once or twice daily.

    Usual Adult Dose for Premature Labor:

    Study - National Institute of Child Health and Human Development (NICHD) - Prevention of Recurrent Preterm Delivery in Women at High Risk: 17-alpha-hydroxyprogesterone caproate (17P) 250 mg IM once weekly starting on the 21st week of gestation through time of delivery or week 36 of gestation.
    Study (n=142) - Reduce Incidence of Spontaneous Preterm Birth in Women at Increased Risk: 100 mg vaginal suppository daily, between 24 and 34 weeks of gestation.

    Usual Adult Dose for Seizures:

    (Study=25) - Catamenial epilepsy [complex partial or secondary generalized motor seizures]:
    200 mg lozenge three times daily administered in relation to pattern of seizure exacerbation during luteal phase of menstrual cycle. For patients with perimenstrual exacerbation, dose was provided on day 23 through day 25 of menstrual cycle. For patients with seizure exacerbation during entire luteal phase, dose was provided on day 15 through day 25 of each menstrual cycle. The desired Progesterone (Hosterona) serum level was between 5 and 25 ng/mL 4 hours after taking the lozenge. All patients continued taking their best antiseizure medication.

    Usual Adult Dose for Perimenopausal Symptoms:

    Progesterone deficiency associated with menopause and perimenopause:
    Progesterone (Hosterona) 1.7% topical cream: Rub 1/4 to 1/2 teaspoonful into the palms of the hands, soles of feet, or other soft area once or twice daily.


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    References

    1. Dailymed."Progesterone: dailymed provides trustworthy information about marketed drugs in the united states. dailymed is the official provider of fda label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
    2. Dailymed."Estradiol hemihydrate: dailymed provides trustworthy information about marketed drugs in the united states. dailymed is the official provider of fda label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
    3. "Progesterone". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).

    Hosterona - Frequently asked Questions

    Can Hosterona be stopped immediately or do I have to stop the consumption gradually to ween off?

    In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.

    It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.

    What other drugs will affect Progesterone (Hosterona)?

    There may be other drugs that can interact with Progesterone (Hosterona). Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

    How should I take Progesterone (Hosterona)?

    Use this medication exactly as it was prescribed for you. Do not use larger amounts, or use it for longer than recommended by your doctor. Follow the directions on your prescription label.

    Progesterone (Hosterona) is sometimes given for only a short period of time, such as 6 to 12 days at a time during each menstrual cycle. Following your dosing schedule is very important for this medication to be effective. Try not to miss any doses.

    This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

    Take the pill form of Progesterone (Hosterona) with a full glass of water.

    Apply Progesterone (Hosterona) cream to the skin as directed by your doctor.

    Progesterone (Hosterona) injection is given as a shot into a muscle. Your doctor, nurse, or other healthcare provider will give you this injection. You may be given instructions on how to use your injections at home. Do not use this medicine at home if you do not fully understand how to give the injection and properly dispose of needles and syringes used in giving the medicine.

    This medication can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are using Progesterone (Hosterona).

    Your doctor will need to see you on a regular basis while you are using this medication. Do not miss any scheduled appointments.

    Store Progesterone (Hosterona) at room temperature away from moisture, heat, and light.

    Who should not take Progesterone (Hosterona)?

    Some forms of this medication may contain peanut oil. Do not use Progesterone (Hosterona) without telling your doctor if you have a peanut allergy.

    Do not use Progesterone (Hosterona) if you have:

    If you have any of these other conditions, you may need a dose adjustment or special tests to safely use Progesterone (Hosterona):

    Do not use Progesterone (Hosterona) without your doctor's consent if you are pregnant. Tell your doctor if you become pregnant during treatment. Use an effective form of birth control while you are using this medication.

    Progesterone (Hosterona) can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

    How should I take Estradiol (Hosterona)?

    Use Estradiol (Hosterona) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

    Ask your health care provider any questions you may have about how to use Estradiol (Hosterona).

    Who should not take Estradiol (Hosterona)?

    Some medical conditions may interact with Estradiol (Hosterona). Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

    Some MEDICINES MAY INTERACT with Estradiol (Hosterona). Tell your health care provider if you are taking any other medicines, especially any of the following:

    This may not be a complete list of all interactions that may occur. Ask your health care provider if Estradiol (Hosterona) may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

    Can Hosterona be taken or consumed while pregnant?

    Please visit your doctor for a recommendation as such case requires special attention.

    Can Hosterona be taken for nursing mothers or during breastfeeding?

    Kindly explain your state and condition to your doctor and seek medical advice from an expert.

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    Reviews

    Following the study conducted by gmedication.com on Hosterona, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Hosterona. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.

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    The information was verified by Dr. Vishal Pawar, MD Pharmacology