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What is the medium of administration of the drug?

Here is the some steps to help you to save money on Histop purchase.


Read drug prescription

It is very important to know about what medicine is given by the doctor, for what condition, and when it needs to be taken in what dose. This information given by the doctor is called Prescription. The patients should be familiar with the medicine prescription, and the details about the medicine before purchasing it and using it. Some medications need not be prescribed by healthcare practitioners and can be purchased and used without prescription by the patients; these are called over-the-counter medications. Read the drug prescription information of Histop before taking it.

What is Histop

Histop is in a group of drugs called HMG CoA reductase inhibitors, or "statins." Histop reduces levels of "bad" cholesterol and triglycerides in the blood, while increasing levels of "good" cholesterol (high-density lipoprotein, or HDL).
Histop is used to lower cholesterol and triglycerides (types of fat) in the blood.
Histop is also used to lower the risk of stroke, heart attack, and other heart complications in people with diabetes, coronary heart disease, or other risk factors.
Histop is used in adults and children who are at least 10 years old.
Histop may also be used for purposes not listed in Histop guide.

Histop side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
In rare cases, Histop can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.
Also call your doctor at once if you have:
  • signs of a kidney problem--little or no urinating; painful or difficult urination; swelling in your feet or ankles; feeling tired or short of breath; or
  • liver problems--nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice.

Common side effects may include:
  • headache;
  • constipation, nausea, stomach pain; or
  • cold symptoms such as stuffy nose, sneezing, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
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Histop dosing

Usual Adult Dose for Prevention of Cardiovascular Disease:

Usual dosage range: 5 to 40 mg orally once a day in the evening
Patients with CHD or at high risk of CHD:
Initial dose: 10 to 20 mg orally once a day in the evening started simultaneously with diet and exercise
Patients at high risk for a CHD event due to existing CHD, diabetes, peripheral vascular disease, history of stroke or other cerebrovascular disease:
Initial dose: 40 mg orally once a day in the evening
Comments:
-Therapy should be individualized according to patient response.
-Lipid determinations should be performed after 4 weeks of therapy and periodically thereafter.
-Due to the increased risk of myopathy, particularly during the first year of treatment, use of the 80 mg dose should be restricted to patients who have been taking 80 mg for 12 months or more without evidence of muscle toxicity.

Usual Adult Dose for Cardiovascular Risk Reduction:

Usual dosage range: 5 to 40 mg orally once a day in the evening
Patients with CHD or at high risk of CHD:
Initial dose: 10 to 20 mg orally once a day in the evening started simultaneously with diet and exercise
Patients at high risk for a CHD event due to existing CHD, diabetes, peripheral vascular disease, history of stroke or other cerebrovascular disease:
Initial dose: 40 mg orally once a day in the evening
Comments:
-Therapy should be individualized according to patient response.
-Lipid determinations should be performed after 4 weeks of therapy and periodically thereafter.
-Due to the increased risk of myopathy (including rhabdomyolysis), particularly during the first year of treatment, use of the 80 mg dose should be restricted to patients who have been taking 80 mg for 12 months or more without evidence of muscle toxicity.

Usual Adult Dose for Homozygous Familial Hypercholesterolemia:

Recommended dose: 40 mg orally once a day in the evening
Comments:
-Simvastatin should be used as an adjunct to other lipid-lowering treatments or alone if such treatments are unavailable.

Usual Pediatric Dose for Heterozygous Familial Hypercholesterolemia:

Less than 10 years: Not recommended
10 years or older:
Initial dose: 10 mg orally once a day in the evening
Maintenance dose: 10 to 40 mg orally once a day in the evening
Maximum dose: 40 mg orally once a day in the evening
Comments:
-Doses should be individualized according to the goal of therapy.
-Dose adjustments should be made at intervals of 4 weeks or more.
-Prior to treatment initiation patients should be placed on a standard cholesterol lowering diet, which should continue during treatment.
Approved indication:
-As an adjunct to diet to reduce total-C, LDL-C, and Apo B levels in adolescent boys and girls who are at least one year postmenarche, 10 to 17 years of age, with HeFH, if after an adequate trial of diet therapy the following findings are present:
1. LDL cholesterol remains 190 mg/dL or greater; or
2. LDL cholesterol remains 160 mg/dL or greater and there is a positive family history of premature cardiovascular disease (CVD) or two or more other CVD risk factors are present in the adolescent patient. The minimum goal of treatment in pediatric and adolescent patients is to achieve a mean LDL-C less than 130 mg/dL.
-The optimal age at which to initiate lipid-lowering therapy to decrease the risk of symptomatic adulthood CAD has not been determined.

Select the most affordable brand or generic drug

Generic drug is the basic drug with an active substance in it, and the name of the generic drug is same as active substance most of the times. Like Acetaminophen/Paracetemol is Generic name and it has different brand names like Tylenol, Acimol, Crocin, Calpol etc. All these Brand names contain the same Paracetemol, but the medications are manufactured by different companies, so the different brand names. Generic drug is always cheaper and affordable, and it can be replaced in place of brand name drug prescribed by the healthcare practitioner. The Generic medicine has same properties as branded medicine in terms of uses, indications, doses, side effects, so no need to worry on that. Just select the most affordable generic or branded medicine.

StrengthQuantityPrice, USDCountry
Afordel 20 mg x 150's $0.29
Afordel 40 mg x 150's $0.37
Afordel film-coated tab 20 mg 150's $46.58Merck
Afordel film-coated tab 40 mg 150's $61.89Merck
Afordel film-coated tab 40 mg 30's $12.38Merck
ASTIN CV 10MG/75MG TABLET 1 strip(s) (10 tablets each) $1.61Micro Labs Ltd
ASTIN tab 40 mg x 10's $2.21Micro Cardicare
ASTIN 20 MG TABLET 1 strip(s) (10 tablets each) $2.62Micro Labs Ltd
5 mg x 10's $0.53
Astin 10mg Tablet $0.08Micro Labs Ltd
ASTIN Capsule/ Tablet / 10mg (10 units) $1.12Microlabs (Cardicare Division)
Lipix 20 mg x 10's $3.00
Lipix 20 mg x 30's $7.20
20 mg x 10's $1.79
LOCHOL tab 20 mg x 10's $1.79Micro Labs
Lochol 20mg TAB / 10 $1.79
Lochol 10mg Tablet $0.04Micro Labs Ltd
LOCHOL 10MG TABLET 1 strip(s) (10 tablets each) $0.36Micro Labs Ltd
Lochol 20 mg x 30's $9.00
Lochol 40 mg x 30's $12.00
Lochol 80 mg x 30's $17.40
10 mg10 Tablet$1.16
Simlip FC 20 mg Tablet $0.21
Simlip FC 10 mg Tablet $0.12
5 mg10 Tablet$0.85
Simvotin 10mg FC-TAB / 10 $1.54
Simvotin 20 mg Tablet $0.26
Simvotin 20mg Tablet $0.34Sun Pharmaceutical Industries Ltd
Simvotin 5+125 Tablet $0.08
SIMVOTIN Capsule/ Tablet / 5mg (10 units) $1.14Ranbaxy
Sinova 10 mg x 20's $11.10
Sinova 5 mg x 20's $6.07
Stavid FC tab 20 mg 100's $30.00Hovid
Stavid 20 mg x 100's $32.00
Vivastin 10 mg x 30's $6.30
Vivastin 20 mg x 30's $7.56
Vivastin 40 mg x 30's $7.92
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References

  1. Dailymed."Simvastatin: dailymed provides trustworthy information about marketed drugs in the united states. dailymed is the official provider of fda label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
  2. "Simvastatin". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
  3. "Simvastatin". http://www.drugbank.ca/drugs/DB0064... (accessed August 28, 2018).

Histop - Frequently asked Questions

Can Histop be stopped immediately or do I have to stop the consumption gradually to ween off?

In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.

It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.

Who should not take Histop?

You should not take Histop if you are allergic to it, if you are pregnant or breast-feeding, or if you have active liver disease.

The following drugs can increase your risk of serious muscle problems if you take them together with Histop. These drugs should not be used while you are taking Histop:

  • cyclosporine;

  • danazol;

  • gemfibrozil;

  • nefazodone;

  • an antibiotic--clarithromycin, erythromycin, telithromycin;

  • antifungal medication--itraconazole, ketoconazole, posaconazole, voriconazole;

  • hepatitis C medications--boceprevir, telaprevir; or

  • HIV/AIDS medication--atazanavir, cobicistat, darunavir, fosamprenavir, indinavir, nelfinavir, ritonavir, saquinavir, tipranavir.

Before you start taking Histop, tell your doctor if you are already using any of these other medicines:

  • lomitapide; or

  • heart medication--amiodarone, amlodipine, diltiazem, dronedarone, ranolazine, verapamil.

To make sure Histop is safe for you, tell your doctor if you have:

  • history of liver disease;

  • history of kidney disease;

  • diabetes;

  • a thyroid disorder; or

  • if you drink more than 2 alcoholic beverages daily.

Histop can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. This condition may be more likely to occur in older adults and in people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid).

FDA pregnancy category X. This medicine can harm an unborn baby or cause birth defects. Do not take Histop if you are pregnant. Stop taking this medication and tell your doctor right away if you become pregnant. Use effective birth control to avoid pregnancy while you are taking Histop.

Histop may pass into breast milk and could harm a nursing baby. Do not breast-feed while you are taking Histop.

How should I take Histop?

Follow all directions on your prescription label. Never take this medicine in larger amounts, or for longer than prescribed. Taking too much of this medication may cause serious or life-threatening side effects.

Histop is usually taken at bedtime or with an evening meal. If you take Histop more than once daily, take it with meals. Your doctor may occasionally change your dose to make sure you get the best results.

While using Histop, you may need frequent blood tests at your doctor's office.

You may need to take Histop on a long-term basis for the treatment of high cholesterol. You may need to stop using Histop for a short time if you have surgery or a medical emergency. Do not stop taking this medicine unless your doctor tells you to.

Histop is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.

Store at room temperature away from moisture, heat, and light.

What other drugs will affect Histop?

Many drugs can interact with Histop. Not all possible interactions are listed here. Tell your doctor about all your medications and any you start or stop using during treatment with Histop, especially:

  • delavirdine;

  • fenofibrate; or

  • fluconazole.

This list is not complete and many other drugs can interact with Histop. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

Can Histop be taken or consumed while pregnant?

Please visit your doctor for a recommendation as such case requires special attention.

Can Histop be taken for nursing mothers or during breastfeeding?

Kindly explain your state and condition to your doctor and seek medical advice from an expert.

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Reviews

Following the study conducted by gmedication.com on Histop, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Histop. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.

Patient reports

Patient reported useful

No survey data has been collected yet


One patient reported side effects

Does the Histop Have Any Side Effects?
Based on the survey report from users of gmedication.com, about It has side effects number of people suffered some side effect after consumption of Histop. All drugs have a portion of undesirable side effects. These effects could be irritations too insignificant for the patient to even notice. However, the side effects of drugs may be determined by several factors like severity of disease and conditions associated with individual patients. However, one of the biggest factors is the dosage consumed. The higher the quantity taken by an individual, the greater the healing effect and the corresponding side effect. All patients have their different intensity of side effects. Ensure you consult your health care provider immediately you notice an unusual side effect affect the consumption of Histop.
Patients%
It has side effects1
100.0%


Patient reported price estimates

No survey data has been collected yet


Two patients reported frequency of use

How often should I take Histop?
According to the survey, gmedication.com reported that users of Histop should take Twice in a day as the primarily recommended frequency. However, patients are advised to follow the dosage as prescribed by their physician religiously. To get the opinions of other patients on the ideal consumption frequency of the medicine, click here.
Patients%
Twice in a day1
50.0%
Once in a day1
50.0%


Two patients reported doses

What is the specific doses you have used?
Histop May come in various doses. In most cases, antibiotics, antihypertensive, pain killers and anti-diabetic drugs available in different doses. Your doctor may prescribe any of the doses based on the severity of the patient's condition. According to our reports, users of gmedication.com used the drugs in the following dosage percentage (Provide dosage percentage). Only a handful of drugs are made in a single or fixed dose. Regular health conditions like fever have similar doses. For instance [acetaminophen, 500mg] was used by the patients surveyed although it comes in different doses.
Patients%
501mg-1g1
50.0%
1-5mg1
50.0%


One patient reported time for results

How long will I use Histop before I begin to notice the effect?
According to the report by users of gmedication.com, about 1 week and a few days was the most common time duration among the participants, before they began to feel relief in their health conditions. It is noteworthy that you may not get the same result with other users within the same time frame. Several factors determine the timeframe; hence we implore you to consult your medical expert to get professional advice on how long you should expect to see improvement while consuming Histop. However, if you wish to get the response of other users on the time effectiveness of using Histop kindly click here
Patients%
1 week1
100.0%


Patient reported administration

No survey data has been collected yet


One patient reported age

Patients%
46-601
100.0%


Patient reviews


There are no reviews yet. Be the first to write one!


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The information was verified by Dr. Harshad Shah, MD Pharmacology