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What is Compazine Spansule

Compazine Spansule is an anti-psychotic medicine in a group of drugs called phenothiazines. It works by changing the actions of chemicals in your brain.
Compazine Spansule oral (taken by mouth) is used to treat psychotic disorders such as schizophrenia. It is also used to treat anxiety, and to control severe nausea and vomiting.
Compazine Spansule may also be used for purposes not listed in Compazine Spansule guide.

Compazine Spansule side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop taking Compazine Spansule and call your doctor at once if you have any of these signs of a serious movement disorder:


Also call your doctor at once if you have:

Common side effects may include:

Side effects such as painful or difficult urination, constipation, and confusion may be more likely in older adults.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)

Compazine Spansule dosing

Usual Adult Dose for Nausea/Vomiting:

Severe nausea and vomiting:
Tablet: 5 to 10 mg 3 to 4 times a day.
Capsule: 15 mg on arising or 10 mg capsule every 12 hours. Daily oral doses above 40 mg should be used only in resistant cases.
Rectal: 25 mg twice a day.
IM: 5 to 10 mg. If necessary, repeat every 3 to 4 hours. Total IM dosage should not exceed 40 mg/day.
IV: 2 1/2 to 10 mg by slow IV injection or infusion at a rate not to exceed 5 mg/min.
A single dose of the drug should not exceed 10 mg. Total IV dosage should not exceed 40 mg/day.
Adult surgery :
IM: 5 to 10 mg injection 1 to 2 hours before induction of anesthesia (repeat once in 30 minutes, if necessary), or to control acute symptoms during and after surgery (repeat once if necessary).
IV: 5 to 10 mg as a slow IV injection or infusion 15 to 30 minutes before induction of anesthesia, or to control acute symptoms during or after surgery. Repeat once if necessary. A single dose of the drug should not exceed 10 mg. The rate of administration should not exceed 5 mg/minute.

Usual Adult Dose for Anxiety:

Non-psychotic anxiety:
Tablet: 5 mg 3 to 4 times a day.
Capsule: 15 mg on arising or 10 mg every 12 hours.
Do not administer in doses of more than 20 mg/day or for longer than 12 weeks.

Usual Adult Dose for Psychosis:

Mild psychotic disorders:
5 to 10 mg orally 3 to 4 times a day.
Moderate to severe psychotic disorders:
Oral: 10 mg orally 3 to 4 times a day. Increase dosage every 2 to 3 days until symptoms are controlled or side effects become bothersome. Some patients respond satisfactorily on 50 to 75 mg/day. In more severe disturbances, optimum dosage is usually 100 to 150 mg/day.
IM: For immediate control of severely disturbed adults, inject an initial dose of 10 to 20 mg deeply into the upper outer quadrant of the buttock. Many patients respond shortly after the first injection. If necessary, repeat the initial dose every 2 to 4 hours to gain control of the patient. More than 3 to 4 doses are seldom necessary. After control is achieved, switch patient to an oral form of the drug at the same dosage level or higher. If, in rare cases, parenteral therapy is needed for a prolonged period, give 10 to 20 mg every 4 to 6 hours.

Select the most affordable brand or generic drug


StrengthQuantityPrice, USDCountry
3 mg7 $0.38
3 mg x 7's $0.38
BUKATEL 3MG TABLET 1 strip(s) (7 tablets each) $0.38Panacea Biotec Ltd
BUKATEL sublingual tab 3 mg x 7's $0.38Panacea
Bukatel 3mg BUC-TAB / 7 $0.38
BUKATEL Capsule/ Tablet / 3mg (7 units) $0.38Panacea Biotec
Bukatel 3mg Tablet $0.05Panacea Biotec Ltd
Bukatel 3 mg Tablet $0.05
5 mg10 $0.25
5 mg x 10's $0.22
Emidoxyn 5mg TAB / 10 $0.22
EMIDOXYN tab 5 mg x 10's $0.22Shreya
EMIDOXYN Capsule/ Tablet / 5mg (10 units) $0.25Shreya Life Sciences
Nausetil 5mg Tablet $0.02Intas Pharmaceuticals Ltd
Nausetil 5 mg Tablet $0.02
5 mg x 10's $0.15
NAUSETIL 5 MG TABLET 1 strip(s) (10 tablets each) $0.18Intas Pharmaceuticals Ltd
Nausetil 5mg TAB / 10 $0.18
NAUSETIL tab 5 mg x 10's $0.18Intas
NAUSETIL inj 12.5 mg x 1 mL x 1ml $0.22Intas
Nausetil 12.5 mg Injection $0.22
Nausetil 12.5mg x 1mL INJ / 1 $0.22
Novomit 4 mg Tablet $0.03
NOVOMIT tab 4 mg x 10's $0.28Ancalima
NOVOMIT inj 2 mg x 1 mL x 2ml $0.30Ancalima
Novomit 10mg Tablet $0.06Numark Ltd
Novomit 10+10 Tablet $0.06
NOVOMIT 10MG TABLET 1 strip(s) (10 tablets each) $0.62Numark Ltd
Stemetil 25 mg Tablet $0.02
STEMETIL tab 5 mg x 10's $0.34AHPL
STEMETIL MD 5 MG TABLET 1 strip(s) (10 tablets each) $0.76Abbott India Ltd
Stemetil 5mg MD-TAB / 21 $1.00

References

  1. Dailymed."Prochlorperazine: dailymed provides trustworthy information about marketed drugs in the united states. dailymed is the official provider of fda label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
  2. "Prochlorperazine". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
  3. "Prochlorperazine". http://www.drugbank.ca/drugs/DB0043... (accessed August 28, 2018).

Compazine Spansule - Frequently asked Questions

Can Compazine Spansule be stopped immediately or do I have to stop the consumption gradually to ween off?

In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.

It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.

What other drugs will affect Compazine Spansule?

Taking this medicine with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects. Ask your doctor before taking Compazine Spansule with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.

Many drugs can interact with Compazine Spansule. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your medications and any you start or stop using during treatment with Compazine Spansule.

Who should not take Compazine Spansule?

You should not use Compazine Spansule if you are allergic to it, or if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications.

Compazine Spansule is not approved for use in psychotic conditions related to dementia. Compazine Spansule may increase the risk of death in older adults with dementia-related conditions.

Long-term use of Compazine Spansule can cause a serious movement disorder that may not be reversible. The longer you take Compazine Spansule, the more likely you are to develop this movement disorder. The risk of this side effect is higher in women and older adults.

Do not give this medication to a child or teenager with a fever, flu symptoms, or an infectious disease such as chickenpox, measles, stomach flu, or an infection of the central nervous system.

To make sure Compazine Spansule is safe for you, tell your doctor if you have:

Tell your doctor if you will be exposed to extreme heat or cold, or to insecticide poisons while you are taking Compazine Spansule.

It is not known whether Compazine Spansule will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

Taking antipsychotic medication during the last 3 months of pregnancy may cause problems in the newborn, such as withdrawal symptoms, breathing problems, feeding problems, fussiness, tremors, and limp or stiff muscles. However, you may have withdrawal symptoms or other problems if you stop taking your medicine during pregnancy. If you become pregnant while taking Compazine Spansule, do not stop taking it without your doctor's advice.

Compazine Spansule can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Compazine Spansule is not for use in children younger than 2 years old or weighing less than 20 pounds. Talk with your doctor before giving this medication to a child who has been ill with a fever or flu symptoms.

How should I take Compazine Spansule?

Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results.

If you take Compazine Spansule long-term, you may need frequent medical tests.

If you need to have an x-ray or CT scan of your spinal column using a dye that is injected into a vein, you may need to temporarily stop taking Compazine Spansule. Be sure the doctor knows ahead of time that you are taking this medication.

Do not stop using Compazine Spansule suddenly after long-term use, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using Compazine Spansule.

Store at room temperature away from moisture, heat, and light.

Can Compazine Spansule be taken or consumed while pregnant?

Please visit your doctor for a recommendation as such case requires special attention.

Can Compazine Spansule be taken for nursing mothers or during breastfeeding?

Kindly explain your state and condition to your doctor and seek medical advice from an expert.

Reviews

Following the study conducted by gmedication.com on Compazine Spansule, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Compazine Spansule. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.

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The information was verified by Dr. Vishal Pawar, MD Pharmacology