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What was the prescribed dosage?

Here is the some steps to help you to save money on Clopidogrel Orion purchase.


Read drug prescription

It is very important to know about what medicine is given by the doctor, for what condition, and when it needs to be taken in what dose. This information given by the doctor is called Prescription. The patients should be familiar with the medicine prescription, and the details about the medicine before purchasing it and using it. Some medications need not be prescribed by healthcare practitioners and can be purchased and used without prescription by the patients; these are called over-the-counter medications. Read the drug prescription information of Clopidogrel Orion before taking it.

What is Clopidogrel Orion

Clopidogrel Orion keeps the platelets in your blood from coagulating to prevent unwanted blood clots that can occur with certain heart or blood vessel conditions.
Clopidogrel Orion is used to prevent blood clots after a recent heart attack or stroke, and in people with certain disorders of the heart or blood vessels.
Clopidogrel Orion may also be used for purposes not listed in Clopidogrel Orion guide.

Clopidogrel Orion side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using Clopidogrel Orion and call your doctor at once if you have any of these serious side effects:
  • nosebleed or other bleeding that will not stop;
  • bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;
  • pale skin, weakness, fever, or jaundice ;
  • easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
  • heart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating; or
  • signs of a stroke--sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
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Clopidogrel Orion dosing

Usual Adult Dose for Ischemic Stroke:

75 mg orally once a day with or without food.
Aspirin therapy should be initiated and continued in combination with Clopidogrel Orion.

Usual Adult Dose for Myocardial Infarction:

75 mg orally once a day with or without food.
Aspirin therapy should be initiated and continued in combination with Clopidogrel Orion.

Usual Adult Dose for Acute Coronary Syndrome -- Prophylaxis:

75 mg orally once a day with or without food.
Aspirin therapy should be initiated and continued in combination with Clopidogrel Orion.

Usual Adult Dose for Peripheral Arterial Disease:

75 mg orally once a day with or without food.
Aspirin therapy should be initiated and continued in combination with Clopidogrel Orion.

Usual Adult Dose for Acute Coronary Syndrome:

Unstable angina, non ST segment elevation myocardial infarction : Initial: 300 mg loading dose, followed by 75 mg once daily for at least 1 month and ideally up to 12 months (in combination with aspirin 75 to 162 mg once daily indefinitely).
ST segment elevation acute myocardial infarction (STEMI): 75 mg once daily (in combination with aspirin 162 to 325 mg initially, followed by 81 to 162 mg/day); Note: The CLARITY TIMI 28 study used a 300 mg loading dose of Clopidogrel Orion (with thrombolysis) demonstrating an improvement in the patency rate of the infarct related artery and reduction in ischemic complications. The duration of therapy was less than 28 days (usually until hospital discharge) unless non primary percutaneous coronary intervention (PCI) was performed.

Usual Adult Dose for Percutaneous Coronary Intervention:

Percutaneous coronary intervention (PCI) for UA/NSTEMI or STEMI:
Loading dose: 300 to 600 mg (600 mg may be preferred for early invasive strategy with UA/NSTEMI) given as early as possible before or at the time of PCI followed by 75 mg once daily. Note: If an initial loading dose of 300 mg was given prior to PCI, a supplemental loading dose of 300 mg (total loading dose: 600 mg) may be administered. For patients with UA/NSTEMI, it has been recommended that the loading dose be given at least 2 hours (or 24 hours in patients unable to take aspirin) prior to PCI.
Higher vs standard maintenance dosing: May consider a maintenance dose of 150 mg once daily for 6 days, then 75 mg once daily thereafter in patients not at high risk for bleeding; however, in another study, in patients with high on treatment platelet reactivity, the use of 150 mg once daily for 6 months did not demonstrate a difference in 6 month incidence of death from cardiovascular causes, nonfatal MI, or stent thrombosis compared to standard dose therapy (Price, 2011).
Duration of Clopidogrel Orion (in combination with aspirin) after stent placement: Premature interruption of therapy may result in stent thrombosis with subsequent fatal and nonfatal MI. With STEMI, Clopidogrel Orion for at least 12 months regardless of stent type (either bare metal or drug eluting stent) is recommended. With UA/NSTEMI, at least 12 months of Clopidogrel Orion is recommended in patients receiving a drug eluting stent (DES) unless the risk of bleeding outweighs the benefits. For bare metal stent (BMS) placement, at least 1 month and ideally up to 12 months duration is recommended unless the risk of bleeding outweighs the benefits; then, a minimum of 2 weeks is recommended. In either setting, a duration greater than 15 months may be considered in patients with DES placement. For patients without ongoing ACS, Clopidogrel Orion should be continued for at least 1 month (for BMS) or at least 12 months (for DES).

Usual Geriatric Dose for Acute Coronary Syndrome:

The American College of Chest Physicians recommends:
Patients over 75 years: 75 mg once daily for up to 28 days

Usual Pediatric Dose for Platelet Aggregation Inhibition:

Note: Safety and efficacy have not been established in pediatric patients; optimal dose is not known; limited dosing information is available; further pediatric studies are needed.
Neonates and Infants up to 2 years: 0.2 mg/kg once daily was found to achieve a mean inhibition of platelet aggregation similar to adults receiving the recommended dose. This dose comes from the PICOLO study which included pediatric patients with a systemic to pulmonary artery shunt, intracardiac or intravascular stent, Kawasaki disease, or arterial graft; 79% of patients received concomitant aspirin; patients less than 2 kg and those born at less than 35 weeks gestational age were excluded.
Children over 2 years of age: Optimal dose is not established; some centers use the following: Initial dose: 1 mg/kg once daily; titrate to response; in general, do not exceed adult dose.

Select the most affordable brand or generic drug

Generic drug is the basic drug with an active substance in it, and the name of the generic drug is same as active substance most of the times. Like Acetaminophen/Paracetemol is Generic name and it has different brand names like Tylenol, Acimol, Crocin, Calpol etc. All these Brand names contain the same Paracetemol, but the medications are manufactured by different companies, so the different brand names. Generic drug is always cheaper and affordable, and it can be replaced in place of brand name drug prescribed by the healthcare practitioner. The Generic medicine has same properties as branded medicine in terms of uses, indications, doses, side effects, so no need to worry on that. Just select the most affordable generic or branded medicine.

StrengthQuantityPrice, USDCountry
300 mg4 $20.00Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
300 mg28 $39.99Canada, Mauritius, Singapore, Turkey, UK, USA
300 mg84 $98.40Canada, India, NZ, Singapore, Turkey, UK, USA
300 mg84 $161.37Australia, Canada, NZ, Singapore, Turkey, UK, USA
300 mg84 $163.00Australia, Canada, India, NZ, Singapore, Turkey, UK, USA
75 mg30 $0.00
75 mg30 $15.00Australia, Canada, India, Mauritius, NZ, Singapore, Turkey, UK, USA
75 mg30 $15.00Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
75 mg30 $24.99Canada, Mauritius, Singapore, Turkey, UK, USA
75 mg90 $39.00Canada, India, NZ, Singapore, Turkey, UK, USA
75 mg90 $39.20Australia, Canada, India, NZ, Singapore, Turkey, UK, USA
75 mg90 $58.58Australia, Canada, India, Mauritius, NZ, Turkey, UK, USA
75 mg100 $36.00Australia, Canada, India, Mauritius, NZ, Singapore, Turkey, UK, USA
75 mg100 $59.00Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
75 mg/150mg100 $70.00Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
75 mg/75mg100 $75.00Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
CLOPIVAS film-coated tab 300 mg x 2's $0.42Cipla
Clopivas 75 mg Tablet $0.06
Clopivas 150mg Tablet $0.10Cipla Ltd
75 mg10 Tablet$0.49
Clotsafe FC 75 mg Tablet $0.05
Diclop 50+500 Tablet $0.02
Norplat 75 mg x 28's $15.27
Placta 75 mg x 3 x 10's $21.98
Winthrop Clopidogrel FC tab 75 mg 14's $8.11Sanofi Pasteur
Winthrop Clopidogrel 75 mg x 14's $11.76
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References

  1. "Clopidogrel". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
  2. "Clopidogrel". http://www.drugbank.ca/drugs/DB0075... (accessed August 28, 2018).
  3. "A74586sno7: the unique ingredient identifier (unii) is an alphanumeric substance identifier from the joint fda/usp substance registration system (srs).". https://www.fda.gov/ForIndustry/Dat... (accessed August 28, 2018).

Clopidogrel Orion - Frequently asked Questions

Can Clopidogrel Orion be stopped immediately or do I have to stop the consumption gradually to ween off?

In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.

It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.

What other drugs will affect Clopidogrel Orion?

Certain other medicines may increase your risk of bleeding. Tell your doctor if you take aspirin, especially if you have had a stroke. Talk to your doctor about whether you should take aspirin with Clopidogrel Orion.

Tell your doctor about all medicines you use, and those you start or stop using during your treatment with Clopidogrel Orion, especially:

  • a blood thinner (warfarin, Coumadin, Jantoven);

  • NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others; or

  • an antidepressant--citalopram, desvenlafaxine, duloxetine, escitalopram, fluoxetine (Prozac), fluvoxamine, milnacipran, paroxetine, sertraline (Zoloft), trazodone, venlafaxine, vilazodone, and others.

This list is not complete. Other drugs may interact with Clopidogrel Orion, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

How should I take Clopidogrel Orion?

Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Clopidogrel Orion can be taken with or without food.

Because Clopidogrel Orion keeps your blood from clotting, it can also make it easier for you to bleed, even from a minor injury. Contact your doctor or seek emergency medical attention if you have bleeding that will not stop.

If you need surgery or dental work, tell the surgeon or dentist ahead of time that you are using Clopidogrel Orion. You may need to stop using the medicine for at least 5 days before having surgery, to prevent excessive bleeding. Follow your doctor's instructions and start taking Clopidogrel Orion again as soon as possible.

You should not stop using this medicine suddenly. Use Clopidogrel Orion regularly even if you feel fine or have no symptoms. Get your prescription refilled before you run out of medicine completely.

Store at room temperature away from moisture and heat.

Who should not take Clopidogrel Orion?

You should not use this medicine if you are allergic to Clopidogrel Orion, or if you have any active bleeding such as a stomach ulcer or bleeding in the brain.

Some medicines can interact with Clopidogrel Orion and should not be used at the same time. Your doctor may need to change your treatment plan if you also take other medicines, especially certain stomach acid reducers (esomeprazole, omeprazole, Nexium, Prilosec).

To make sure Clopidogrel Orion is safe for you, tell your doctor if you have:

  • a bleeding or blood clotting disorder, such as TTP (thrombocytopenic purpura) or hemophilia;

  • a history of stroke, including TIA ("mini-stroke");

  • a stomach ulcer or ulcerative colitis;

  • kidney disease; or

  • if you are allergic to medicines like Clopidogrel Orion, such as prasugrel, ticagrelor, or ticlopidine.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether Clopidogrel Orion passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

Can Clopidogrel Orion be taken or consumed while pregnant?

Please visit your doctor for a recommendation as such case requires special attention.

Can Clopidogrel Orion be taken for nursing mothers or during breastfeeding?

Kindly explain your state and condition to your doctor and seek medical advice from an expert.

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Reviews

Following the study conducted by gmedication.com on Clopidogrel Orion, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Clopidogrel Orion. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.

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The information was verified by Dr. Harshad Shah, MD Pharmacology