Climen

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• Read drug prescription
• What is Estradiol (Climen)
• Important safety information:
• Estradiol (Climen) side effects
• Select the most affordable brand or generic drug
• Frequently asked Questions
• Who should not take Estradiol (Climen)?
• How should I take Estradiol (Climen)?
• Climen reviews

Read drug prescription

consists of Cyproterone, Estradiol.

Estradiol (Climen)

What is Estradiol (Climen)

Treating itching, burning, and dryness in or around the vaginal area in women past menopause.
Estradiol (Climen) is a vaginal estrogen tablet. It works by increasing the amount of estrogen in the body in certain women who do not produce enough on their own.

Important safety information:

• Estradiol may increase the risk of stroke, heart attack, blood clots, high blood pressure, or similar problems. The risk may be greater if you smoke.
• Estradiol (Climen) may cause dark skin patches on your face (melasma). Exposure to the sun may make these patches darker, and you may need to avoid prolonged sun exposure and sunlamps. Consult your doctor regarding the use of sunscreens and protective clothing.
• Tell your doctor or dentist that you take Estradiol (Climen) before you receive any medical or dental care, emergency care, or surgery. If you will be having surgery or will be confined to a chair or bed for a long period of time (eg, a long plane flight), notify your doctor at least 4 to 6 weeks beforehand. You may need to stop taking Estradiol (Climen) or take other special precautions for a period of time.
• If you wear contact lenses and you develop problems with them, contact your doctor.
• Diabetes patients - Estradiol (Climen) may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
• Estradiol (Climen) may interfere with certain lab tests. Be sure your doctor and lab personnel know you are using Estradiol (Climen).
• Lab tests, including physical exams, cholesterol levels, and blood pressure, may be performed while you use Estradiol (Climen). You should have breast and pelvic exams and a Pap test at least once a year. You should also have periodic mammograms as determined by your doctor. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
• Follow your doctors instructions for examining your breasts, and report any lumps immediately.
• Talk with your doctor regularly (eg, every 3 to 6 months) about whether you need to continue taking Estradiol (Climen).
• Use Estradiol (Climen) with caution in the ELDERLY; they may be more sensitive to its effects.
• Estradiol (Climen) is not approved for use in CHILDREN; safety and effectiveness in children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: Do not use Estradiol (Climen) if you are pregnant. If you think you may be pregnant, contact your doctor right away. Estradiol (Climen) is found in breast milk. If you are or will be breast-feeding while you use Estradiol (Climen), check with your doctor. Discuss any possible risks to your baby.

Estradiol (Climen) side effects

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Breast pain or tenderness; diarrhea; hair loss; headache; mild fluid retention; mild nausea or vomiting; spotting or breakthrough bleeding; stomach cramps or bloating.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); abnormal vaginal bleeding; breast lumps or pain; bulging eyes; calf pain, swelling, or tenderness; chest pain; coughing up blood; fainting; mental or mood changes (eg, depression); migraine headache; new or worsening memory problems; new or worsening vaginal pain or irritation; pelvic pain; severe or persistent dizziness or headache; severe or persistent stomach or back pain (with or without nausea or vomiting); shortness of breath; swelling of the hands or feet; symptoms of heart attack (eg, chest, jaw, or arm pain; sudden, severe nausea or vomiting; shortness of breath; sudden, unusual sweating); symptoms of liver problems (eg, dark urine, pale stools, yellowing of the skin or eyes); symptoms of stroke (eg, one-sided weakness, slurred speech, confusion); unusual vaginal discharge/itching/odor; vision loss or other vision changes; vomiting.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

Active ingredients: Cyproterone/Estradiol

Select the most affordable brand or generic drug

Strength	Quantity	Price, USD	Country
Clim?ne
Climen 28
Climen 28 28's		$21.69
Climen Ciclica
Climene
Cyproterone/Estradiol
Elamax
Femilar
Pausene Ciclica

References

1. Dailymed."Estradiol hemihydrate: dailymed provides trustworthy information about marketed drugs in the united states. dailymed is the official provider of fda label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
2. "Estradiol". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
3. "Estradiol". http://www.drugbank.ca/drugs/DB0078... (accessed August 28, 2018).

Climen - Frequently asked Questions

Can Climen be stopped immediately or do I have to stop the consumption gradually to ween off?

In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.

It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.

Who should not take Estradiol (Climen)?

Some medical conditions may interact with Estradiol (Climen). Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a condition called hereditary angioedema
• if you have a history of breast lumps, breast disease, or an abnormal mammogram, or if a member of your family has had breast cancer
• if you have a vaginal infection or a history of uterus problems (eg, fibroids, endometriosis, abnormal vaginal bleeding, cancer), or you have had your uterus removed (hysterectomy)
• if you have a history of asthma, depression, memory problems, diabetes, seizures, gallbladder disease, pancreatitis, heart problems, high blood cholesterol or triglyceride levels, high blood calcium levels, high blood pressure, low blood levels of parathyroid hormone, or porphyria
• if you have a history of kidney or liver problems, yellowing of the skin or eyes, cancer, lupus, migraines, thyroid problems, or chorea (jerky, involuntary movements of the face, arms, or legs)
• if you smoke, use tobacco, are very overweight, will be having surgery, or will be confined to a bed or chair for a period of time
• if a member of your family has had high cholesterol or triglyceride levels, blood clots (eg, in the leg or lung), lupus, or has been very overweight

Some MEDICINES MAY INTERACT with Estradiol (Climen). Tell your health care provider if you are taking any other medicines, especially any of the following:

• Azole antifungals (eg, ketoconazole), macrolide antibiotics (eg, erythromycin), or protease inhibitors (eg, ritonavir) because they may increase the risk of estradiol's side effects
• Barbiturates (eg, phenobarbital), carbamazepine, hydantoins (eg, phenytoin), rifamycins (eg, rifampin), or St. John's wort because they may decrease estradiol's effectiveness
• Thyroid hormones (eg, levothyroxine) because their effectiveness may be decreased by Estradiol (Climen)

This may not be a complete list of all interactions that may occur. Ask your health care provider if Estradiol (Climen) may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How should I take Estradiol (Climen)?

Use Estradiol (Climen) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• An extra patient leaflet is available with Estradiol (Climen). Talk to your pharmacist if you have questions about this information.
• To use, tear off a single applicator, separate the plastic wrap, and remove the applicator from the plastic wrap.
• Select the position for vaginal insertion that is most comfortable for you (lying on the bed, squatting, or standing with one leg on a stool).
• Place the finger of one hand on the applicator plunger. Use the other hand to gently and comfortably guide the applicator into the vagina. If the tablet falls out of the applicator before inserting the filled applicator, use a new applicator with a fresh tablet.
• Insert the tablet as far into the vagina as it can comfortably go without force, or until half of the applicator is in your vagina, whichever is less.
• After inserting the filled applicator, gently press the plunger until you hear a click and the plunger is fully depressed. This will eject the tablet inside your vagina. The tablet will dissolve slowly over several hours.
• After depressing the plunger, gently remove the applicator and throw it away. Do not reuse the applicator.
• You may use Estradiol (Climen) at any time of the day. However, you should use it at the same time of day each time you use it.
• Eating grapefruit or drinking grapefruit juice may increase the risk of estradiol's side effects. Talk to your doctor before including grapefruit or grapefruit juice in your diet while you are taking Estradiol (Climen).
• If you miss a dose of Estradiol (Climen), use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Estradiol (Climen).

Can Climen be taken or consumed while pregnant?

Please visit your doctor for a recommendation as such case requires special attention.

Can Climen be taken for nursing mothers or during breastfeeding?

Kindly explain your state and condition to your doctor and seek medical advice from an expert.

Reviews

Following the study conducted by gmedication.com on Climen, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Climen. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.

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The information was verified by Dr. Vishal Pawar, MD Pharmacology