What is the medium of administration of the drug?
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What is Arrow Simva

Arrow Simva is in a group of drugs called HMG CoA reductase inhibitors, or "statins." Arrow Simva reduces levels of "bad" cholesterol and triglycerides in the blood, while increasing levels of "good" cholesterol (high-density lipoprotein, or HDL).
Arrow Simva is used to lower cholesterol and triglycerides (types of fat) in the blood.
Arrow Simva is also used to lower the risk of stroke, heart attack, and other heart complications in people with diabetes, coronary heart disease, or other risk factors.
Arrow Simva is used in adults and children who are at least 10 years old.
Arrow Simva may also be used for purposes not listed in Arrow Simva guide.

Arrow Simva side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
In rare cases, Arrow Simva can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.
Also call your doctor at once if you have:

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
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Arrow Simva dosing

Usual Adult Dose for Prevention of Cardiovascular Disease:

Usual dosage range: 5 to 40 mg orally once a day in the evening
Patients with CHD or at high risk of CHD:
Initial dose: 10 to 20 mg orally once a day in the evening started simultaneously with diet and exercise
Patients at high risk for a CHD event due to existing CHD, diabetes, peripheral vascular disease, history of stroke or other cerebrovascular disease:
Initial dose: 40 mg orally once a day in the evening
Comments:
-Therapy should be individualized according to patient response.
-Lipid determinations should be performed after 4 weeks of therapy and periodically thereafter.
-Due to the increased risk of myopathy, particularly during the first year of treatment, use of the 80 mg dose should be restricted to patients who have been taking 80 mg for 12 months or more without evidence of muscle toxicity.

Usual Adult Dose for Cardiovascular Risk Reduction:

Usual dosage range: 5 to 40 mg orally once a day in the evening
Patients with CHD or at high risk of CHD:
Initial dose: 10 to 20 mg orally once a day in the evening started simultaneously with diet and exercise
Patients at high risk for a CHD event due to existing CHD, diabetes, peripheral vascular disease, history of stroke or other cerebrovascular disease:
Initial dose: 40 mg orally once a day in the evening
Comments:
-Therapy should be individualized according to patient response.
-Lipid determinations should be performed after 4 weeks of therapy and periodically thereafter.
-Due to the increased risk of myopathy (including rhabdomyolysis), particularly during the first year of treatment, use of the 80 mg dose should be restricted to patients who have been taking 80 mg for 12 months or more without evidence of muscle toxicity.

Usual Adult Dose for Homozygous Familial Hypercholesterolemia:

Recommended dose: 40 mg orally once a day in the evening
Comments:
-Simvastatin should be used as an adjunct to other lipid-lowering treatments or alone if such treatments are unavailable.

Usual Pediatric Dose for Heterozygous Familial Hypercholesterolemia:

Less than 10 years: Not recommended
10 years or older:
Initial dose: 10 mg orally once a day in the evening
Maintenance dose: 10 to 40 mg orally once a day in the evening
Maximum dose: 40 mg orally once a day in the evening
Comments:
-Doses should be individualized according to the goal of therapy.
-Dose adjustments should be made at intervals of 4 weeks or more.
-Prior to treatment initiation patients should be placed on a standard cholesterol lowering diet, which should continue during treatment.
Approved indication:
-As an adjunct to diet to reduce total-C, LDL-C, and Apo B levels in adolescent boys and girls who are at least one year postmenarche, 10 to 17 years of age, with HeFH, if after an adequate trial of diet therapy the following findings are present:
1. LDL cholesterol remains 190 mg/dL or greater; or
2. LDL cholesterol remains 160 mg/dL or greater and there is a positive family history of premature cardiovascular disease (CVD) or two or more other CVD risk factors are present in the adolescent patient. The minimum goal of treatment in pediatric and adolescent patients is to achieve a mean LDL-C less than 130 mg/dL.
-The optimal age at which to initiate lipid-lowering therapy to decrease the risk of symptomatic adulthood CAD has not been determined.

Select the most affordable brand or generic drug


StrengthQuantityPrice, USDCountry
Avastin 5mg Tablet $0.05Orchid Chemicals & Pharmaceuticals Ltd
AVASTIN Capsule/ Tablet / 5mg (10 units) $0.54Aglowmed Limited
AVASTIN Capsule/ Tablet / 20mg (10 units) $1.01Aglowmed Limited
Euvasten 10 mg x 30's $9.60
Euvasten 20 mg x 30's $13.50
Euvasten 40 mg x 30's $16.20
Forcad 10 mg x 30's $9.24
Forcad film-coated tab 10 mg 30's $9.24Corbridge
Forcad 20 mg x 30's $13.35
Forcad film-coated tab 20 mg 30's $13.35Corbridge
Forcad 40 mg x 30's $15.54
Forcad film-coated tab 40 mg 30's $15.54Corbridge
10 mg90 $126.69Barbados, Canada, NZ, UK
20 mg30 $46.50Barbados, Canada, NZ, UK
80 mg90 $143.40Barbados, Canada, NZ, UK
Normofat 10 mg x 30's $1.04
Pontizoc 5 5 mg x 3 x 10's $7.84
Pontizoc 10 10 mg x 3 x 10's $1.72
10 mg28 $32.35Canada, UK
10 mg84 $53.85Barbados, Canada, NZ, UK
10 mg90 $22.40Canada, India, NZ, Singapore, Turkey, UK, USA
10 mg90 $56.41Australia, Canada, NZ, Singapore, Turkey, UK, USA
10 mg90 $56.98Australia, Canada, India, NZ, Singapore, Turkey, UK, USA
10 mg112 $39.00Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
10 mg112 $45.00Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
20 mg28 $21.56Barbados, Canada, NZ, UK
20 mg30 $47.00
20 mg84 $20.00Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
20 mg84 $46.20Barbados, Canada, NZ, UK
20 mg90 $20.30Australia, Canada, India, NZ, Singapore, Turkey, UK, USA
20 mg90 $60.00Barbados, Canada, NZ, UK
20 mg100 $168.68Canada, UK
20 mg112 $45.00Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
20 mg112 $55.00Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
20 mg224 $55.00Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
40 mg30 $65.01Canada, UK
40 mg60 $18.89Australia, Canada, India, NZ, Singapore, Turkey, UK, USA
40 mg60 $34.65Australia, Canada, NZ, Singapore, Turkey, UK, USA
40 mg84 $37.00Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
40 mg84 $37.32Canada, Mauritius, Singapore, Turkey, UK, USA
40 mg90 $72.82Australia, Canada, India, Mauritius, NZ, Turkey, UK, USA
40 mg90 $394.70USA
40 mg100 $438.00USA
40 mg112 $29.90Australia, Canada, NZ, Singapore, Turkey
5 mg90 $16.47Australia, Canada, India, NZ, Singapore, Turkey, UK, USA
5 mg90 $16.99Canada, Mauritius, Singapore, Turkey, UK, USA
5 mg90 $39.90USA
5 mg100 $42.00Australia, Canada, India, Mauritius, NZ, Singapore, Turkey, UK, USA
80 mg28 $30.18Barbados, Canada, NZ, UK
80 mg30 $65.01Canada, UK
80 mg45 $44.92Australia, Canada, India, NZ, Singapore, Turkey, UK, USA
80 mg84 $50.00Australia, Canada, Mauritius, NZ, Singapore, Turkey, UK, USA
80 mg84 $64.68Barbados, Canada, NZ, UK
80 mg90 $33.10Australia, Canada, India, NZ, Singapore, Turkey, UK, USA
80 mg90 $79.00Australia, Canada, India, Mauritius, NZ, Turkey, Singapore, UK, USA
80 mg100 $168.68Canada, UK
Generic Zocor 5mg - 28 Tablets $34.99
Generic Simvastatin 20mg - 28 Tablets $38.99
Generic Simvastatin 20mg - 84 Tablets $69.95
Generic Zocor 10mg - 112 Tablets $94.95
Jamp-Simvastatin 5 mg Tablet $0.59
Ran-Simvastatin 5 mg Tablet $0.59
Novo-Simvastatin 10 mg Tablet $1.17
Sandoz Simvastatin 10 mg Tablet $1.17
Co Simvastatin 40 mg Tablet $1.45
Mylan-Simvastatin 20 mg Tablet $1.45
Novo-Simvastatin 80 mg Tablet $1.45
Pms-Simvastatin 40 mg Tablet $1.45
Ratio-Simvastatin 20 mg Tablet $1.45
Sandoz Simvastatin 80 mg Tablet $1.45
Zocor 10 mg tablet $2.89
Vytorin 10-80 mg tablet $4.63
Vytorin 10-40 mg tablet $5.05
10 mg10 Tablet$0.41
SIMVOFIX tab 10 mg x 10's $0.41Bal Pharma (Servetus)
SIMVOFIX 10 MG TABLET 1 strip(s) (10 tablets each) $0.71Bal Pharma Ltd
Simvofix 40 mg Tablet $0.10
SIMVOFIX Capsule/ Tablet / 40mg (10 units) $1.05Bal Pharma
Vidastat tab 10 mg 30's $113.50Therapharma
Vidastat tab 20 mg 30's $168.50Therapharma
Vidastat 40 mg x 30's $20.29
Vidastat 80 mg x 30's $20.29
Vidastat tab 40 mg 30's $25.66Therapharma
Vidastat tab 80 mg 30's $25.66Therapharma
Vidastat 20 mg x 100's $54.29
Vidastat tab 20 mg 100's $68.66Therapharma
Vidastat 20 mg x 30's $7.73
Vidastat 10 mg x 30's $4.88
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References

  1. Dailymed."Simvastatin: dailymed provides trustworthy information about marketed drugs in the united states. dailymed is the official provider of fda label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
  2. "Simvastatin". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
  3. "Simvastatin". http://www.drugbank.ca/drugs/DB0064... (accessed August 28, 2018).

Arrow Simva - Frequently asked Questions

Can Arrow Simva be stopped immediately or do I have to stop the consumption gradually to ween off?

In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.

It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.

What other drugs will affect Arrow Simva?

Many drugs can interact with Arrow Simva. Not all possible interactions are listed here. Tell your doctor about all your medications and any you start or stop using during treatment with Arrow Simva, especially:

This list is not complete and many other drugs can interact with Arrow Simva. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

Who should not take Arrow Simva?

You should not take Arrow Simva if you are allergic to it, if you are pregnant or breast-feeding, or if you have active liver disease.

The following drugs can increase your risk of serious muscle problems if you take them together with Arrow Simva. These drugs should not be used while you are taking Arrow Simva:

Before you start taking Arrow Simva, tell your doctor if you are already using any of these other medicines:

To make sure Arrow Simva is safe for you, tell your doctor if you have:

Arrow Simva can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. This condition may be more likely to occur in older adults and in people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid).

FDA pregnancy category X. This medicine can harm an unborn baby or cause birth defects. Do not take Arrow Simva if you are pregnant. Stop taking this medication and tell your doctor right away if you become pregnant. Use effective birth control to avoid pregnancy while you are taking Arrow Simva.

Arrow Simva may pass into breast milk and could harm a nursing baby. Do not breast-feed while you are taking Arrow Simva.

How should I take Arrow Simva?

Follow all directions on your prescription label. Never take this medicine in larger amounts, or for longer than prescribed. Taking too much of this medication may cause serious or life-threatening side effects.

Arrow Simva is usually taken at bedtime or with an evening meal. If you take Arrow Simva more than once daily, take it with meals. Your doctor may occasionally change your dose to make sure you get the best results.

While using Arrow Simva, you may need frequent blood tests at your doctor's office.

You may need to take Arrow Simva on a long-term basis for the treatment of high cholesterol. You may need to stop using Arrow Simva for a short time if you have surgery or a medical emergency. Do not stop taking this medicine unless your doctor tells you to.

Arrow Simva is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.

Store at room temperature away from moisture, heat, and light.

Can Arrow Simva be taken or consumed while pregnant?

Please visit your doctor for a recommendation as such case requires special attention.

Can Arrow Simva be taken for nursing mothers or during breastfeeding?

Kindly explain your state and condition to your doctor and seek medical advice from an expert.

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Reviews

Following the study conducted by gmedication.com on Arrow Simva, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Arrow Simva. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.

Patient reports

Patient reported useful

No survey data has been collected yet


Patient reported side effects

No survey data has been collected yet


Patient reported price estimates

No survey data has been collected yet


Patient reported frequency of use

No survey data has been collected yet


One patient reported doses

What is the specific doses you have used?
Arrow Simva May come in various doses. In most cases, antibiotics, antihypertensive, pain killers and anti-diabetic drugs available in different doses. Your doctor may prescribe any of the doses based on the severity of the patient's condition. According to our reports, users of gmedication.com used the drugs in the following dosage percentage (Provide dosage percentage). Only a handful of drugs are made in a single or fixed dose. Regular health conditions like fever have similar doses. For instance [acetaminophen, 500mg] was used by the patients surveyed although it comes in different doses.
Patients%
6-10mg1
100.0%


Patient reported time for results

No survey data has been collected yet


Patient reported administration

No survey data has been collected yet


Patient reported age

No survey data has been collected yet


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The information was verified by Dr. Vishal Pawar, MD Pharmacology