Anset blocks the actions of chemicals in the body that can trigger nausea and vomiting. Anset is used to prevent nausea and vomiting that may be caused by surgery or by medicine to treat cancer. Anset injection is not for preventing nausea or vomiting that is caused by factors other than chemotherapy or surgery. Anset may be used for purposes not listed in Anset guide.
How is Anset given?
Anset is injected into a vein through an IV. A healthcare provider will give you this injection. Anset is usually given just before your surgery begins, or within 2 hours after surgery. To prevent nausea and vomiting caused by chemotherapy, Anset is given 30 minutes before the start of chemotherapy. A second and third dose of Anset are sometimes given 4 hours and 8 hours after the first dose.
What should I avoid after receiving Anset?
This medicine may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.
Anset side effects
Get emergency medical help if you have any of these signs of an allergic reaction: rash, hives; fever, chills, difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have:
headache with chest pain and severe dizziness, fainting, fast or pounding heartbeats;
blurred vision or temporary vision loss ;
severe constipation;
a light-headed feeling, like you might pass out;
little or no urinating;
high levels of serotonin in the body--agitation, hallucinations, fever, fast heart rate, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination, fainting; or
severe skin reaction--fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Common side effects may include:
diarrhea or constipation;
drowsiness;
fever; or
headache.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. See also: Side effects (in more detail)
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Anset dosing
Usual Adult Dose for Nausea/Vomiting -- Chemotherapy Induced:
Recommended dose: Three 0.15 mg/kg doses. The first dose is infused over 15 minutes beginning 30 minutes before the start of emetogenic chemotherapy. Subsequent doses (0.15 mg/kg up to a maximum of 16 mg per dose) are administered 4 and 8 hours after the first dose. Alternative therapies: Oral soluble film dosage form: Highly emetogenic cancer chemotherapy: 24 mg given successively as three 8 mg films administered 30 minutes before the start of single-day highly emetogenic chemotherapy, including cisplatin greater than or equal to 50 mg/m2. Moderately emetogenic cancer chemotherapy: One 8 mg soluble film given 2 times a day. The first dose should be administered 30 minutes before the start of emetogenic chemotherapy, with a subsequent dose 8 hours after the first dose.
Usual Adult Dose for Nausea/Vomiting:
Recommended dose: Three 0.15 mg/kg doses (up to a maximum of 16 mg per dose). The first dose is infused over 15 minutes beginning 30 minutes before the start of emetogenic chemotherapy. Subsequent doses (0.15 mg/kg up to a maximum of 16 mg per dose) are administered 4 and 8 hours after the first dose. Alternative therapies: Oral soluble film dosage form: Highly emetogenic cancer chemotherapy: 24 mg given successively as three 8 mg films administered 30 minutes before the start of single-day highly emetogenic chemotherapy, including cisplatin greater than or equal to 50 mg/m2. Moderately emetogenic cancer chemotherapy: One 8 mg soluble film given 2 times a day. The first dose should be administered 30 minutes before the start of emetogenic chemotherapy, with a subsequent dose 8 hours after the first dose.
Usual Adult Dose for Nausea/Vomiting -- Postoperative:
4 mg IV over 2 to 5 minutes, or IM, immediately before induction of anesthesia or postoperatively if nausea or vomiting occurs within 2 hours after surgery. Alternatively, 4 mg (undiluted) may be administered intramuscularly as a single injection for adults. While recommended as a fixed dose for patients weighing more than 40 kg, few patients above 80 kg have been studied. Patients who do not achieve adequate control of postoperative nausea and vomiting following a single, prophylactic, preinduction, intravenous dose of Anset 4 mg, administration of a second intravenous dose of 4 mg Anset postoperatively does not provide additional control of nausea and vomiting. 16 mg orally 1 hour before induction of anesthesia. Oral soluble film dosage form: 16 mg given as successively as two 8 mg oral soluble films 1 hour before induction of anesthesia.
Usual Adult Dose for Nausea/Vomiting--Radiation Induced:
8 mg orally every 8 hours, give the first dose 1 to 2 hours prior to radiotherapy. Oral soluble film dosage form: One 8 mg soluble film given 3 times a day. For total body irradiation: One 8 mg soluble film given 1 to 2 hours before each fraction of radiotherapy administered each day. For single high-dose fraction radiotherapy to the abdomen: One 8 mg oral soluble film given 1 to 2 hours before radiotherapy, with subsequent doses every 8 hours after the first dose for 1 to 2 days after completion of radiotherapy. For daily fractionated radiotherapy to the abdomen: One 8 mg oral soluble film given 1 to 2 hours before radiotherapy, with subsequent doses every 8 hours after the first dose for each day radiotherapy is given.
Usual Adult Dose for Pruritus:
Study - Induced by Intrathecal Fentanyl 8 mg IV before spinal anesthesia.
Usual Adult Dose for Alcohol Dependence:
Study (n=321) - Early onset alcoholism 4 mcg/kg two times daily.
Usual Adult Dose for Postanesthetic Shivering:
Study 8 mg IV, 3 to 5 minutes before the induction of anesthesia.
Usual Pediatric Dose for Nausea/Vomiting -- Postoperative:
Child 1 month to 12 years: 40 kg or less: 0.1 mg/kg single dose IV, administered over 2 to 5 minutes, immediately prior to or following anesthesia induction, or postoperatively if nausea and/or vomiting present shortly after surgery. 40 kg or more: 4 mg single dose IV, administered over 2 to 5 minutes, immediately prior to or following anesthesia induction, or postoperatively if nausea and/or vomiting present shortly after surgery.
Usual Pediatric Dose for Nausea/Vomiting -- Chemotherapy Induced:
Child 6 months to 18 years: 0.15 mg/kg as an IV infusion (over 15 minutes) administered 30 minutes before the start of emetogenic therapy, then at 4 and 8 hours after the first dose, respectively. 4 to 11 years: 4 mg orally given 30 minutes before the start of emetogenic therapy, then 4 mg orally 4 and 8 hours after the first dose. Thereafter, 4 mg orally every 8 hours for 1 to 2 days after emetogenic therapy is complete. 11 years or older:: 8 mg orally 3 times daily, or 24 mg orally once daily. Oral soluble film dosage form: Use of Anset oral soluble films is not indicated for treatment of nausea and vomiting associated with highly emetogenic cancer chemotherapy in pediatric patients. For prevention of nausea and vomiting associated with moderately emetogenic cancer chemotherapy: For pediatric patients 12 years of age and older, the dosage is the same as for adults. For pediatric patients 4 through 11 years of age, the dosage is one 4 mg oral soluble film given 3 times a day. The first dose should be administered 30 minutes before the start of emetogenic chemotherapy, with subsequent doses 4 and 8 hours after the first dose. One 4 mg oral soluble film should be administered 3 times a day (every 8 hours) for 1 to 2 days after completion of chemotherapy.
Usual Pediatric Dose for Gastroenteritis:
Study (n=145) - Control of emesis during the ED phase of oral rehydration: 6 months to 12 months: 1.6 mg orally every 8 hours 1 year to 3 years: 3.2 mg orally every 8 hours 4 years or older: 4 mg orally every 8 hours Dosage was administered 15 minutes before the start of oral rehydration.
Dailymed."Ondansetron: dailymed provides trustworthy information about marketed drugs in the united states. dailymed is the official provider of fda label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
Can Anset be stopped immediately or do I have to stop the consumption gradually to ween off?
In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.
It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.
Who should not take Anset?
You should not use this medicine if you are allergic to Anset, or if you are also using apomorphine.
To make sure Anset is safe for you, tell your doctor if you have:
liver disease;
heart disease, congestive heart failure, a heart rhythm disorder;
an electrolyte imbalance (such as low levels of potassium or magnesium in your blood);
a personal or family history of Long QT syndrome; or
if you take a diuretic or "water pill."
FDA pregnancy category B. Anset is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether Anset passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
What other drugs will affect Anset?
There are many other medicines that can increase your risk of heart rhythm problems if you use them together with Anset.
Tell your doctor about all medicines you use, and those you start or stop using during your treatment with Anset, especially:
anagrelide;
droperidol;
methadone;
an antibiotic--azithromycin, clarithromycin, erythromycin, levofloxacin, moxifloxacin, pentamidine;
medicine to treat a psychiatric disorder--chlorpromazine, haloperidol, pimozide, thioridazine.
This list is not complete. Other drugs may interact with Anset, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
How should I take Anset?
You should not use Anset if you are also using apomorphine (Apokyn).
Can Anset be taken or consumed while pregnant?
Please visit your doctor for a recommendation as such case requires special attention.
Can Anset be taken for nursing mothers or during breastfeeding?
Kindly explain your state and condition to your doctor and seek medical advice from an expert.
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Reviews
Following the study conducted by gmedication.com on Anset, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Anset. We, therefore, urge readers not to base their medical judgment strictly on the result of this study but on test/diagnosis duly conducted by a certified medical practitioners or physician.
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